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Invitrogen
LBX1 Polyclonal Antibody
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Product Details
PA5-40601
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human LBX1
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2608557
Product Specific Information
Peptide sequence: LPLAGRALLS QTSPLCALEE LASKTFKGLE VSVLQAAEGR DGMTIFGQRQ
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Target Information
LBX1 is the transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord.This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: lady bird-like homeobox; ladybird homeobox homolog 1; Ladybird homeobox protein homolog 1; Transcription factor LBX1; transcription factor similar to D. melanogaster homeodomain protein lady bird late
Gene Aliases: homeobox; HPX-6; HPX6; LBX1; LBX1H
UniProt ID: (Human) P52954
Entrez Gene ID: (Human) 10660
heart looping
transcription, DNA-templated
muscle organ development
negative regulation of cell proliferation
anatomical structure morphogenesis
spinal cord motor neuron differentiation
regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification
negative regulation of neuron differentiation
neuron fate determination
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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