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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • MAP1LC3A/B/C Antibodies

          Proteintech

          LC3 Polyclonal Antibody, CoraLite® 594

          View all (4) MAP1LC3A/B/C antibodies
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          Datasheet
          Protocols
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          Cite LC3 Polyclonal Antibody, CoraLite® 594

          • Antibody Testing Data (1)
          LC3 Antibody in Flow Cytometry (Flow)
          Group 53 Created with Sketch.
          LC3 Antibody in Flow Cytometry (Flow)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          LC3 Antibody (CL59414600100UL) in Flow

          1X10^6 HeLa cells were intracellularly stained with 0.4 µg CoraLite 594 Anti-Human LC3 (Product # CL59414600100UL)) (red), or 0.4 µg Control Antibody. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          LC3 Antibody in Flow Cytometry (Flow)

          Product Details

          CL59414600100UL

          Applications
          Tested Dilution
          Publications

          Flow Cytometry (Flow)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Conjugate

          CoraLite® 594 CoraLite® 594 CoraLite® 594

          Excitation/Emission Max

          593/614 nm

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 0.5% BSA, 50% glycerol

          Contains

          0.05% ProClin 300

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles, store in dark

          Shipping conditions

          Wet ice

          Target Information

          MAP1LC3A (Microtubule Associated Protein 1 Light Chain 3 Alpha) is a Protein Coding gene. Diseases associated with MAP1LC3A include Machado-Joseph Disease and Neurodegeneration With Brain Iron Accumulation. Among its related pathways are Selective autophagy and Mitophagy. Gene Ontology (GO) annotations related to this gene include microtubule binding and phosphatidylethanolamine binding. An important paralog of this gene is MAP1LC3B. MAP1LC3B (Microtubule Associated Protein 1 Light Chain 3 Beta) is a Protein Coding gene. Diseases associated with MAP1LC3B include Liver Carcinoma In Situ and Pheochromocytoma. Among its related pathways are Early SARS-CoV-2 Infection Events and Selective autophagy. Gene Ontology (GO) annotations related to this gene include microtubule binding. MAP1LC3C (Microtubule Associated Protein 1 Light Chain 3 Gamma) is a Protein Coding gene. Diseases associated with MAP1LC3C include Machado-Joseph Disease. Among its related pathways are Selective autophagy and Ferroptosis.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Autophagy-related protein LC3 A; Autophagy-related protein LC3 B; Autophagy-related protein LC3 C; Autophagy-related ubiquitin-like modifier LC3 A; Autophagy-related ubiquitin-like modifier LC3 B; Autophagy-related ubiquitin-like modifier LC3 C; LC3-like protein 2; MAP1 light chain 3-like protein 1; MAP1 light chain 3-like protein 2; MAP1 light chain 3-like protein 3; MAP1A/1B light chain 3 A; MAP1A/1B light chain 3 B; MAP1A/MAP1B LC3 A; MAP1A/MAP1B LC3 B; MAP1A/MAP1B LC3 C; MAP1A/MAP1B light chain 3 A; MAP1A/MAP1B light chain 3 B; MAP1A/MAP1B light chain 3 C; Microtubule-associated protein 1 light chain 3 alpha; Microtubule-associated protein 1 light chain 3 beta; Microtubule-associated protein 1 light chain 3 gamma; microtubule-associated proteins 1A/1B light chain 3; Microtubule-associated proteins 1A/1B light chain 3A; Microtubule-associated proteins 1A/1B light chain 3B; Microtubule-associated proteins 1A/1B light chain 3C

          View more View less

          Gene Aliases: 1010001C15Rik; 1010001H21Rik; 4922501H04Rik; Atg8; ATG8E; ATG8F; ATG8J; LC3; LC3A; LC3B; LC3C; MAP1A/1BLC3; MAP1ALC3; MAP1BLC3; Map1lc3; MAP1LC3A; MAP1LC3B; MAP1LC3B-a; MAP1LC3C; Mpl3; zbs559

          View more View less

          UniProt ID: (Human) Q9H492, (Human) Q9GZQ8, (Human) Q9BXW4, (Rat) Q6XVN8, (Mouse) Q91VR7, (Rat) Q62625, (Mouse) Q9CQV6

          View more View less

          Entrez Gene ID: (Human) 84557, (Human) 81631, (Human) 440738, (Rat) 362245, (Mouse) 66734, (Rat) 64862, (Mouse) 67443

          View more View less

          Function(s)
          protein binding phospholipid binding microtubule binding phosphatidylethanolamine binding ubiquitin protein ligase binding molecular_function GABA receptor binding tubulin binding protein domain specific binding
          Process(es)
          autophagosome assembly mitophagy cellular response to nitrogen starvation macroautophagy regulation of mitophagy autophagy positive regulation of protein binding nucleophagy membrane fusion positive regulation of mucus secretion
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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