Product References
Diets Differently Regulate Tumorigenesis in Young E0771 Syngeneic Breast Cancer Mouse Model.
Journal of clinical medicine
Thangavel H,Lizardo K,Dhanyalayam D,De Assis S,Nagajyothi JF
PA1-16931 was used in Immunohistochemistry to suggest that diet composition, adipogenesis, and loss of body fat likely regulate the pathogenesis of BC in a manner that differs between young and post-menopausal subjects.
Wed Jan 04 00:00:00 UTC 2023
Metformin preconditioning protects against myocardial stunning and preserves protein translation in a mouse model of cardiac arrest.
Journal of molecular and cellular cardiology plus
Rutledge CA,Lagranha C,Chiba T,Redding K,Stolz DB,Goetzman E,Sims-Lucas S,Kaufman BA
Published figure using LC3A/LC3B polyclonal antibody (Product # PA1-16931) in Western Blot
Thu Jun 01 00:00:00 UTC 2023
Infliximab Ameliorates Methotrexate-Induced Nephrotoxicity in Experimental Rat Model: Impact on Oxidative Stress, Mitochondrial Biogenesis, Apoptotic and Autophagic Machineries.
Cell biochemistry and biophysics
Wasfey EF,Shaaban M,Essam M,Ayman Y,Kamar S,Mohasseb T,Rozik R,Khaled H,Eladly M,Elissawi M,Bassem A,Elshora SZ,Radwan SM
PA1-16931 was used in Immunohistochemistry to suggest that Infliximab provides protection against Methotrexate (MTX)-induced nephrotoxicity which could be elucidated by its antioxidant, anti-inflammatory, anti-apoptotic and anti-autophagic effects as well as upregulating mitochondrial biogenesis.
Fri Dec 01 00:00:00 UTC 2023
Infliximab Ameliorates Methotrexate-Induced Nephrotoxicity in Experimental Rat Model: Impact on Oxidative Stress, Mitochondrial Biogenesis, Apoptotic and Autophagic Machineries.
Cell biochemistry and biophysics
Wasfey EF,Shaaban M,Essam M,Ayman Y,Kamar S,Mohasseb T,Rozik R,Khaled H,Eladly M,Elissawi M,Bassem A,Elshora SZ,Radwan SM
PA1-16931 was used in Immunohistochemistry to suggest that Infliximab provides protection against Methotrexate (MTX)-induced nephrotoxicity which could be elucidated by its antioxidant, anti-inflammatory, anti-apoptotic and anti-autophagic effects as well as upregulating mitochondrial biogenesis.
Fri Dec 01 00:00:00 UTC 2023
Optogenetically engineered Ca2+ oscillation-mediated DRP1 activation promotes mitochondrial fission and cell death.
Journal of cell science
Lai YS,Chang CC,Chen YY,Nguyen TMH,Xu J,Chen YC,Chang YF,Wang CY,Chen PS,Lin SC,Peng IC,Tsai SJ,Chiu WT
PA1-16931 was used in Western Blotting to provide an effective and innovative approach to altering Ca2+ signaling for controlling mitochondrial fission with a more precise resolution than pharmacological approaches in the temporal dimension.
Thu Jun 15 00:00:00 UTC 2023
Free fatty acid treatment of mouse preimplantation embryos demonstrates contrasting effects of palmitic acid and oleic acid on autophagy.
American journal of physiology. Cell physiology
Leung ZCL,Abu Rafea B,Watson AJ,Betts DH
PA1-16931 was used in Immunohistochemistry-immunofluorescence to investigated the effects of palmitic acid (PA) and oleic acid (OA), alone and in combination, on autophagy during preimplantation development in vitro.
Sun May 01 00:00:00 UTC 2022
Free fatty acid treatment of mouse preimplantation embryos demonstrates contrasting effects of palmitic acid and oleic acid on autophagy.
American journal of physiology. Cell physiology
Leung ZCL,Abu Rafea B,Watson AJ,Betts DH
PA1-16931 was used in Immunohistochemistry-immunofluorescence to investigated the effects of palmitic acid (PA) and oleic acid (OA), alone and in combination, on autophagy during preimplantation development in vitro.
Sun May 01 00:00:00 UTC 2022
Cx43-mediated sorting of miRNAs into extracellular vesicles.
EMBO reports
Martins-Marques T,Costa MC,Catarino S,Simoes I,Aasen T,Enguita FJ,Girao H
PA1-16931 was used in Western Blotting to ascribe another biological role to Cx43, that is, the selective incorporation of miRNAs into EV, which potentially modulates multiple biological processes in target cells and may have implications for human health and disease.
Tue Jul 05 00:00:00 UTC 2022
Cx43-mediated sorting of miRNAs into extracellular vesicles.
EMBO reports
Martins-Marques T,Costa MC,Catarino S,Simoes I,Aasen T,Enguita FJ,Girao H
PA1-16931 was used in Western Blotting to ascribe another biological role to Cx43, that is, the selective incorporation of miRNAs into EV, which potentially modulates multiple biological processes in target cells and may have implications for human health and disease.
Tue Jul 05 00:00:00 UTC 2022
Penta-O-Galloyl-β-D-Glucose in Pistacia integerrima Targets AMPK-ULK1 and ERK/STAT3 Signaling Axes to Induce ROS-Independent Autophagic Cell Death in Human Lung Cancer Cells.
Frontiers in pharmacology
Balkrishna A,Mulay VP,Verma S,Srivastava J,Lochab S,Varshney A
PA1-16931 was used in ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to propose PGG as a potential AMPK activator and STAT3 inhibitor that can be exploited further in developing adjuvant chemotherapeutics against lung cancer.
Sat Aug 06 00:00:00 UTC 2022
Penta-O-Galloyl-β-D-Glucose in Pistacia integerrima Targets AMPK-ULK1 and ERK/STAT3 Signaling Axes to Induce ROS-Independent Autophagic Cell Death in Human Lung Cancer Cells.
Frontiers in pharmacology
Balkrishna A,Mulay VP,Verma S,Srivastava J,Lochab S,Varshney A
PA1-16931 was used in ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to propose PGG as a potential AMPK activator and STAT3 inhibitor that can be exploited further in developing adjuvant chemotherapeutics against lung cancer.
Sat Aug 06 00:00:00 UTC 2022
Diane-35 and Metformin Induce Autophagy and Apoptosis in Polycystic Ovary Syndrome Women with Early-Stage Endometrial Carcinoma.
Genes
Liu Y,Wang Y,Yao D,Chen X,Zhang F,Feng Y,Li X
PA1-16931 was used in Western Blot to support the use of Diane-35 and metformin combination therapy for patients with PCOS and early EC.
Wed Jan 12 00:00:00 UTC 2022
Diane-35 and Metformin Induce Autophagy and Apoptosis in Polycystic Ovary Syndrome Women with Early-Stage Endometrial Carcinoma.
Genes
Liu Y,Wang Y,Yao D,Chen X,Zhang F,Feng Y,Li X
PA1-16931 was used in Western Blot to support the use of Diane-35 and metformin combination therapy for patients with PCOS and early EC.
Wed Jan 12 00:00:00 UTC 2022
Inhibition of Ubiquitin-Specific Protease-13 Improves Behavioral Performance in Alpha-Synuclein Expressing Mice.
International journal of molecular sciences
Liu X,Balaraman K,Lynch CC,Hebron M,Shah PK,Hu S,Stevenson M,Wolf C,Moussa C
PA1-16931 was used in Western Blotting to studiy the role of USP13 in knockout mice expressing lentiviral human alpha-synuclein and investigate the impact of a small molecule inhibitor of USP13, BK50118-C, on alpha-synuclein pathology and animal behavior.
Sat Jul 23 00:00:00 UTC 2022
Mingmu Xiaoyao granules regulate the PI3K/Akt/mTOR signaling pathway to reduce anxiety and depression and reverse retinal abnormalities in rats.
Frontiers in pharmacology
Ma Q,Zhou J,Yang Z,Xue Y,Xie X,Li T,Yang Y
PA1-16931 was used in ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to show that MMXY may effectively improve retinal morphology and function as well as anxiety and depression-like behaviors in CUMS rats by regulating the PI3K/Akt/mTOR signaling pathway.
Tue Mar 28 00:00:00 UTC 2023
Inhibition of Calcineurin/NFAT Signaling Blocks Oncogenic H-Ras Induced Autophagy in Primary Human Keratinocytes.
Frontiers in cell and developmental biology
Wang S,Qian H,Zhang L,Liu P,Zhuang D,Zhang Q,Bai F,Wang Z,Yan Y,Guo J,Huang J,Wu X
Published figure using LC3A/LC3B polyclonal antibody (Product # PA1-16931) in Western Blot
Fri Aug 06 00:00:00 UTC 2021
REV1 Inhibition Enhances Radioresistance and Autophagy.
Cancers
Ikeh KE,Lamkin EN,Crompton A,Deutsch J,Fisher KJ,Gray M,Argyle DJ,Lim WY,Korzhnev DM,Hadden MK,Hong J,Zhou P,Chatterjee N
Published figure using LC3A/LC3B polyclonal antibody (Product # PA1-16931) in Western Blot
Thu Oct 21 00:00:00 UTC 2021
Sinoporphyrin sodium is a promising sensitizer for photodynamic and sonodynamic therapy in glioma.
Oncology reports
An YW,Liu HQ,Zhou ZQ,Wang JC,Jiang GY,Li ZW,Wang F,Jin HT
PA1-16931 was used in Western Blotting to explore the antitumor effects of sinoporphyrin sodium (DVDMS)‚mediated photodynamic therapy (PDT) and sonodynamic therapy (SDT) in glioma, and to reveal the underlying mechanisms.
Thu Oct 01 00:00:00 UTC 2020
Early Intracellular Trafficking and Subsequent Activity of Programmed Cell Death in Channel Catfish Macrophages Infected with Edwardsiella ictaluri.
Microorganisms
Dubytska LP,Thune RL
PA1-16931 was used in Immunocytochemistry to study trafficking and programmed cell death in Edwardsiella ictaluri-infected catfish macrophages.
Sat Oct 24 00:00:00 UTC 2020
Early Intracellular Trafficking and Subsequent Activity of Programmed Cell Death in Channel Catfish Macrophages Infected with Edwardsiella ictaluri.
Microorganisms
Dubytska LP,Thune RL
PA1-16931 was used in Immunocytochemistry to study trafficking and programmed cell death in Edwardsiella ictaluri-infected catfish macrophages.
Sat Oct 24 00:00:00 UTC 2020
Autophagy activation in circulating proangiogenic cells aggravates AKI in type I diabetes mellitus.
American journal of physiology. Renal physiology
Schwarze K,Kribben A,Ritter O,Müller GA,Patschan D
PA1-16931 was used in Western Blotting to utilize two established autophagy inducers for pharmacological preconditioning of so-called proangiogenic cells (PACs) in PAC treatment of diabetic AKI.
Mon Oct 01 00:00:00 UTC 2018
Pazopanib Reduces Phosphorylated Tau Levels and Alters Astrocytes in a Mouse Model of Tauopathy.
Journal of Alzheimer's disease : JAD
Javidnia M,Hebron ML,Xin Y,Kinney NG,Moussa CE
Published figure using LC3A/LC3B polyclonal antibody (Product # PA1-16931) in Western Blot
Mon Apr 09 00:00:00 UTC 2018
Autophagy negatively regulates pro-osteogenic activity in human aortic valve interstitial cells.
The Journal of surgical research
Deng XS,Meng X,Venardos N,Song R,Yamanaka K,Fullerton D,Jaggers J
PA1-16931 was used in Immunohistochemistry-immunofluorescence to suggest that upregulation of autophagy may prevent the progression of calcific aortic valve disease.
Sun Oct 01 00:00:00 UTC 2017
Autophagy negatively regulates pro-osteogenic activity in human aortic valve interstitial cells.
The Journal of surgical research
Deng XS,Meng X,Venardos N,Song R,Yamanaka K,Fullerton D,Jaggers J
PA1-16931 was used in Immunohistochemistry-immunofluorescence to suggest that upregulation of autophagy may prevent the progression of calcific aortic valve disease.
Sun Oct 01 00:00:00 UTC 2017
Coordinated Upregulation of Mitochondrial Biogenesis and Autophagy in Breast Cancer Cells: The Role of Dynamin Related Protein-1 and Implication for Breast Cancer Treatment.
Oxidative medicine and cellular longevity
Zou P,Liu L,Zheng LD,Payne KK,Manjili MH,Idowu MO,Zhang J,Schmelz EM,Cheng Z
PA1-16931 was used in western blot to study mitochondrial biogenesis and mitophagy in cancer cells
Mon Mar 13 00:00:00 UTC 2017
Amelioration of neuronal cell death in a spontaneous obese rat model by dietary restriction through modulation of ubiquitin proteasome system.
The Journal of nutritional biochemistry
Shruthi K,Reddy SS,Reddy PY,Shivalingam P,Harishankar N,Reddy GB
PA1-16931 was used in western blot to characterize amelioration of neuronal cell death in a rat model of spontaneous obesity that is dietary-restricted through modulation of ubiquitin proteasome system
Fri Jul 01 00:00:00 UTC 2016
MEK5/ERK5 signaling inhibition increases colon cancer cell sensitivity to 5-fluorouracil through a p53-dependent mechanism.
Oncotarget
Pereira DM,Simões AE,Gomes SE,Castro RE,Carvalho T,Rodrigues CM,Borralho PM
PA116931 was used in western blot to assess the contribution of MEK5/ERK5 signaling in the sensitivity of colon cancer cells to 5-fluorouracil
Tue Jun 07 00:00:00 UTC 2016
MicroRNA-34a Modulates Neural Stem Cell Differentiation by Regulating Expression of Synaptic and Autophagic Proteins.
Molecular neurobiology
Morgado AL,Xavier JM,Dionísio PA,Ribeiro MF,Dias RB,Sebastião AM,Solá S,Rodrigues CM
PA1-16931 was used in western blot to identify Syt1 and Atg9a as targets of miR-34a during neuronal stem cell differentiation
Fri Feb 12 00:00:00 UTC 2016
K63 linked ubiquitin chain formation is a signal for HIF1A degradation by Chaperone-Mediated Autophagy.
Scientific reports
Ferreira JV,Soares AR,Ramalho JS,Pereira P,Girao H
PA1-16931 was used in western blot to report that K63 ubiquitination is required for chaperone-mediated autophagy degradation of HIF1A in vitro and in vivo.
Mon May 11 00:00:00 UTC 2015
Mitochondrial translocation of p53 modulates neuronal fate by preventing differentiation-induced mitochondrial stress.
Antioxidants & redox signaling
Xavier JM,Morgado AL,Solá S,Rodrigues CM
PA1-16931 was used in immunocytochemistry and western blot to study the role of p53 mitochondrial translocation in modulating mitochondrial stress induced by differentiation and the significance for neuronal cell fate
Mon Sep 01 00:00:00 UTC 2014
Mitochondrial translocation of p53 modulates neuronal fate by preventing differentiation-induced mitochondrial stress.
Antioxidants & redox signaling
Xavier JM,Morgado AL,Solá S,Rodrigues CM
PA1-16931 was used in immunocytochemistry and western blot to study the role of p53 mitochondrial translocation in modulating mitochondrial stress induced by differentiation and the significance for neuronal cell fate
Mon Sep 01 00:00:00 UTC 2014
Mitochondrial translocation of p53 modulates neuronal fate by preventing differentiation-induced mitochondrial stress.
Antioxidants & redox signaling
Xavier JM,Morgado AL,Solá S,Rodrigues CM
PA1-16931 was used in immunocytochemistry and western blot to study the role of p53 mitochondrial translocation in modulating mitochondrial stress induced by differentiation and the significance for neuronal cell fate
Mon Sep 01 00:00:00 UTC 2014
STUB1/CHIP is required for HIF1A degradation by chaperone-mediated autophagy.
Autophagy
Ferreira JV,Fôfo H,Bejarano E,Bento CF,Ramalho JS,Girão H,Pereira P
PA1-16931 was used in Immunocytochemistry to show that HIF1A can be targeted for degradation in the lysosome by CMA and this targeting is dependent on its interaction with the ubiquitin ligase STUB1.
Sun Sep 01 00:00:00 UTC 2013
Amyloid β peptides promote autophagy-dependent differentiation of mouse neural stem cells: Aβ-mediated neural differentiation.
Molecular neurobiology
Fonseca MB,Solá S,Xavier JM,Dionísio PA,Rodrigues CM
PA1-16931 was used in western blot to study the ability of different beta-amyloid peptides to drive murine neural stem cell differentiation and the role played by autophagy
Sun Dec 01 00:00:00 UTC 2013
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.jpg?time=20250104?time=20250104 "LC3A/LC3B Antibody (PA1-16931) in WB, ICC/IF")
