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Abnova
LEFTY1 Monoclonal Antibody (3B5)
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Product Details
H00010637-M11
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
3B5
Immunogen
LEFTY1 (NP_066277, 145 a.a. approximately 250 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: VTVEWLRVRD DGSNRTSLID SRLVSVHESG WKAFDVTEAV NFWQQLSRPR QPLLLQVSVQ REHLGPLASG AHKLVRFASQ GAPAGLGEPQ LELHTLDLGD YGAQGD
Target Information
This gene encodes a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Left-right determination factor 1; Left-right determination factor B; left-right determination, factor B; Protein lefty-1; Protein lefty-B
Gene Aliases: LEFTB; LEFTY1; LEFTYB; UNQ278/PRO317
UniProt ID: (Human) O75610
Entrez Gene ID: (Human) 10637
negative regulation of transcription from RNA polymerase II promoter
heart morphogenesis
transforming growth factor beta receptor signaling pathway
determination of left/right symmetry
positive regulation of pathway-restricted SMAD protein phosphorylation
cell growth
regulation of apoptotic process
regulation of MAPK cascade
cell development
SMAD protein signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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