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Bioss
LEPREL2 Polyclonal Antibody
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Product Details
BS-6068R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human LEPREL2, amino acids 351-450.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene belongs to the leprecan family of proteoglycans, which function as collagen prolyl hydroxylases that are required for proper collagen biosynthesis, folding and assembly. This protein, like other family members, is thought to reside in the endoplasmic reticulum. Epigenetic inactivation of this gene is associated with breast and other cancers, suggesting that it may function as a tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: gene rich cluster, B; leprecan-like 2; Leprecan-like protein 2; procollagen-proline 3-dioxygenase; Prolyl 3-hydroxylase 3; Protein B
Gene Aliases: BC016431; GRCB; HSU47926; LEPREL2; P3H3
UniProt ID: (Human) Q8IVL6, (Mouse) Q8CG70
Entrez Gene ID: (Human) 10536, (Rat) 297595, (Mouse) 14789
iron ion binding
procollagen-proline 3-dioxygenase activity
L-ascorbic acid binding
molecular_function
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
metal ion binding
dioxygenase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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