Proteintech

LGALS3BP Polyclonal Antibody

LGALS3BP Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 10

LGALS3BP Antibody (10281-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol ) fixed HepG2 cells using 10281-1-AP (LGALS3BP antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

LGALS3BP Antibody in Immunohistochemistry (Paraffin) (IHC (P))

LGALS3BP Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

10281-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 10 publications 10 publications

Immunohistochemistry (IHC)

View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 4 publications 4 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

LGALS3BP Fusion Protein Ag0294 (6-221 aa encoded by BC002403)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.35 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: LFWVWLLVA GTQGVNDGDM RLADGGATNQ GRVEIFYRGQ WGTVCDNLWD LTDASVVCRA LGFENATQAL GRAAFGQGSG PIMLDEVQCT GTEASLADCK SLGWLKSNCR HERDAGVVCT NETRSTHTLD LSRELSEALG QIFDSQRGCD LSISVNVQGE DALGFCGHTV ILTANLEAQA LWKEPGSNVT MSVDAECVPM VRDLLRYFYS RRIDITL (6-221 aa encoded by BC002403)

Target Information

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Spatial proteomics reveals secretory pathway disturbances caused by neuropathy-associated TECPR2.

Nature communications

Nalbach K,Schifferer M,Bhattacharya D,Ho-Xuan H,Tseng WC,Williams LA,Stolz A,Lichtenthaler SF,Elazar Z,Behrends C

Thu Feb 16 00:00:00 UTC 2023

A new liver regeneration molecular mechanism involving hepatic stellate cells, Kupffer cells, and glucose-regulated protein 78 as a new hepatotrophic factor.

Journal of hepato-biliary-pancreatic sciences

Hagiwara K,Harimoto N,Yamanaka T,Ishii N,Yokobori T,Tsukagoshi M,Watanabe A,Araki K,Yoshizumi T,Shirabe K

Wed Feb 01 00:00:00 UTC 2023

A new liver regeneration molecular mechanism involving hepatic stellate cells, Kupffer cells, and glucose-regulated protein 78 as a new hepatotrophic factor.

Journal of hepato-biliary-pancreatic sciences

Hagiwara K,Harimoto N,Yamanaka T,Ishii N,Yokobori T,Tsukagoshi M,Watanabe A,Araki K,Yoshizumi T,Shirabe K

Wed Feb 01 00:00:00 UTC 2023

Prognostic Value and Biological Function of Galectins in Malignant Glioma.

Frontiers in oncology

Zhu H,Liu D,Cheng L,Liu J,Wang G,Li H,Zhang Y,Mi H,Zhang S,Shu K,Yu X

Sat Jul 16 00:00:00 UTC 2022

Prognostic Value and Biological Function of Galectins in Malignant Glioma.

Frontiers in oncology

Zhu H,Liu D,Cheng L,Liu J,Wang G,Li H,Zhang Y,Mi H,Zhang S,Shu K,Yu X

Sat Jul 16 00:00:00 UTC 2022

Reciprocal association of serum Mac-2 binding protein and HDL-cholesterol concentrations.

Clinica chimica acta; international journal of clinical chemistry

Uekita H,Yamamoto H,Niinaga R,Yamane N,Yoshii M,Yamauchi-Takihara K,Kihara S

Sat May 01 00:00:00 UTC 2021

MZT2A promotes NSCLC viability and invasion by increasing Akt phosphorylation via the MOZART2 domain.

Cancer science

Wang H,Jiang X,Cheng Y,Ren H,Hu Y,Zhang Y,Su H,Zou Z,Wang Q,Liu Z,Zhang J,Qiu X

Tue Jun 01 00:00:00 UTC 2021

Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2.

Nature communications

Wang C,Li Y,Yan S,Wang H,Shao X,Xiao M,Yang B,Qin G,Kong R,Chen R,Zhang N

Mon Jun 22 00:00:00 UTC 2020

Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex.

PLoS pathogens

Xu G,Xia Z,Deng F,Liu L,Wang Q,Yu Y,Wang F,Zhu C,Liu W,Cheng Z,Zhu Y,Zhou L,Zhang Y,Lu M,Liu S

Thu Aug 01 00:00:00 UTC 2019

Increased Mac-2 binding protein glycan isomer in patients at risk for late nonrelapse mortality after HSCT.

Blood advances

Akahoshi Y,Nakasone H,Kawamura K,Kusuda M,Kawamura S,Takeshita J,Yoshino N,Misaki Y,Yoshimura K,Gomyo A,Tanihara A,Tamaki M,Kimura SI,Kako S,Kanda Y

Tue Nov 12 00:00:00 UTC 2019

Increased LGALS3BP promotes proliferation and migration of oral squamous cell carcinoma via PI3K/AKT pathway.

Cellular signalling

Zhang X,Ding H,Lu Z,Ding L,Song Y,Jing Y,Hu Q,Dong Y,Ni Y

Fri Nov 01 00:00:00 UTC 2019

Increased LGALS3BP promotes proliferation and migration of oral squamous cell carcinoma via PI3K/AKT pathway.

Cellular signalling

Zhang X,Ding H,Lu Z,Ding L,Song Y,Jing Y,Hu Q,Dong Y,Ni Y

Fri Nov 01 00:00:00 UTC 2019

Marked elevation of serum M2BP-adiponectin complex in men with coronary artery disease.

Atherosclerosis

Niinaga R,Yamamoto H,Yoshii M,Uekita H,Yamane N,Kochi I,Matsumoto A,Matsuoka T,Kihara S

Sat Oct 01 00:00:00 UTC 2016

Marked elevation of serum M2BP-adiponectin complex in men with coronary artery disease.

Atherosclerosis

Niinaga R,Yamamoto H,Yoshii M,Uekita H,Yamane N,Kochi I,Matsumoto A,Matsuoka T,Kihara S

Sat Oct 01 00:00:00 UTC 2016

Shoc2-tranduced ERK1/2 motility signals--Novel insights from functional genomics.

Cellular signalling

Jeoung M,Jang ER,Liu J,Wang C,Rouchka EC,Li X,Galperin E

Sun May 01 00:00:00 UTC 2016

Shoc2-tranduced ERK1/2 motility signals--Novel insights from functional genomics.

Cellular signalling

Jeoung M,Jang ER,Liu J,Wang C,Rouchka EC,Li X,Galperin E

Sun May 01 00:00:00 UTC 2016

Composition and characteristics of distinct macrophage subpopulations in the mouse thymus.

Molecular medicine reports

Liu LT,Lang ZF,Li Y,Zhu YJ,Zhang JT,Guo SF,Wang JX,Wang HW,Xu YD

Sat Jun 01 00:00:00 UTC 2013

Composition and characteristics of distinct macrophage subpopulations in the mouse thymus.

Molecular medicine reports

Liu LT,Lang ZF,Li Y,Zhu YJ,Zhang JT,Guo SF,Wang JX,Wang HW,Xu YD

Sat Jun 01 00:00:00 UTC 2013

A galectin-3-dependent pathway upregulates interleukin-6 in the microenvironment of human neuroblastoma.

Cancer research

Silverman AM,Nakata R,Shimada H,Sposto R,DeClerck YA

Tue May 01 00:00:00 UTC 2012

A galectin-3-dependent pathway upregulates interleukin-6 in the microenvironment of human neuroblastoma.

Cancer research

Silverman AM,Nakata R,Shimada H,Sposto R,DeClerck YA

Tue May 01 00:00:00 UTC 2012

O-GlcNAc-specific antibody CTD110.6 cross-reacts with N-GlcNAc2-modified proteins induced under glucose deprivation.

PloS one

Isono T

Tue Apr 19 00:00:00 UTC 2011

O-GlcNAc-specific antibody CTD110.6 cross-reacts with N-GlcNAc2-modified proteins induced under glucose deprivation.

PloS one

Isono T

Tue Apr 19 00:00:00 UTC 2011

SILAC-based quantitative proteomic approach to identify potential biomarkers from the esophageal squamous cell carcinoma secretome.

Cancer biology & therapy

Kashyap MK,Harsha HC,Renuse S,Pawar H,Sahasrabuddhe NA,Kim MS,Marimuthu A,Keerthikumar S,Muthusamy B,Kandasamy K,Subbannayya Y,Prasad TS,Mahmood R,Chaerkady R,Meltzer SJ,Kumar RV,Rustgi AK,Pandey A

Fri Oct 15 00:00:00 UTC 2010

SILAC-based quantitative proteomic approach to identify potential biomarkers from the esophageal squamous cell carcinoma secretome.

Cancer biology & therapy

Kashyap MK,Harsha HC,Renuse S,Pawar H,Sahasrabuddhe NA,Kim MS,Marimuthu A,Keerthikumar S,Muthusamy B,Kandasamy K,Subbannayya Y,Prasad TS,Mahmood R,Chaerkady R,Meltzer SJ,Kumar RV,Rustgi AK,Pandey A

Fri Oct 15 00:00:00 UTC 2010

Proteomics study of medullary thyroid carcinomas expressing RET germ-line mutations: identification of new signaling elements.

Molecular carcinogenesis

Gorla L,Mondellini P,Cuccuru G,Miccichè F,Cassinelli G,Cremona M,Pierotti MA,Lanzi C,Bongarzone I

Sun Mar 01 00:00:00 UTC 2009

Proteomics study of medullary thyroid carcinomas expressing RET germ-line mutations: identification of new signaling elements.

Molecular carcinogenesis

Gorla L,Mondellini P,Cuccuru G,Miccichè F,Cassinelli G,Cremona M,Pierotti MA,Lanzi C,Bongarzone I

Sun Mar 01 00:00:00 UTC 2009

Proteomic discovery of 21 proteins expressed in human plasma-derived but not platelet-derived microparticles.

Thrombosis and haemostasis

Smalley DM,Root KE,Cho H,Ross MM,Ley K

Mon Jan 01 00:00:00 UTC 2007

Proteomic discovery of 21 proteins expressed in human plasma-derived but not platelet-derived microparticles.

Thrombosis and haemostasis

Smalley DM,Root KE,Cho H,Ross MM,Ley K

Mon Jan 01 00:00:00 UTC 2007

Galectin 3-binding protein is a potential contaminant of recombinantly produced factor IX.

Haemophilia : the official journal of the World Federation of Hemophilia

Blostein M,Cuerquis J,Galipeau J

Thu Nov 01 00:00:00 UTC 2007

Galectin 3-binding protein is a potential contaminant of recombinantly produced factor IX.

Haemophilia : the official journal of the World Federation of Hemophilia

Blostein M,Cuerquis J,Galipeau J

Thu Nov 01 00:00:00 UTC 2007

Bioinformatics

Protein Aliases: Basement membrane autoantigen p105; Galectin-3-binding protein; L3 antigen; Lectin; lectin galactoside-binding soluble 3 binding protein; Lectin galactoside-binding soluble 3-binding protein; lectin, galactoside binding soluble 3 binding protein; lectin, galactoside-binding, soluble, 3 binding protein; mac-2 BP; Mac-2-binding protein; MAC2BP; serum protein 90K; transport and golgi organization 10 homolog B; Tumor-associated antigen 90K

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Gene Aliases: 90K; BTBD17B; CyCAP; gp90; LGALS3BP; M2BP; MAC-2-BP; TANGO10B

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UniProt ID: (Human) Q08380

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Entrez Gene ID: (Human) 3959

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Function(s)

scavenger receptor activity

Process(es)

platelet degranulation receptor-mediated endocytosis cellular defense response cell adhesion signal transduction

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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LGALS3BP Polyclonal Antibody

LGALS3BP Antibody (10281-1-AP) in ICC/IF

Product Details

10281-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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