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LGALS3BP Antibody (PA5-100001) in ICC/IF
Immunocytochemistry analysis of LGALS3BP in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with LGALS3BP polyclonal antibody (Product # PA5-100001) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-100001
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human LGALS3BP(Accession Q08380), corresponding to amino acid residues F471-K521.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2815531
Product Specific Information
Antibody detects endogenous levels of total LGALS3BP.
Target Information
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Basement membrane autoantigen p105; CyCAP; Cyp-C-associated protein; Galectin-3-binding protein; L3 antigen; Lectin; lectin galactoside-binding soluble 3 binding protein; Lectin galactoside-binding soluble 3-binding protein; lectin, galactoside binding soluble 3 binding protein; lectin, galactoside-binding, soluble, 3 binding protein; mac-2 BP; Mac-2-binding protein; MAC2BP; mama; peptidylprolyl isomerase C-associated protein; Protein MAMA; serum protein 90K; transport and golgi organization 10 homolog B; Tumor-associated antigen 90K
Gene Aliases: 90K; BTBD17B; CyCAP; gp90; LGALS3BP; M2BP; MAC-2-BP; MAC-2BP; Mama; Ppicap; TANGO10B
UniProt ID: (Human) Q08380, (Mouse) Q07797
Entrez Gene ID: (Human) 3959, (Mouse) 19039
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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