Invitrogen

LILRB3 Monoclonal Antibody (326414)

Advanced Verification

4 Published Figures

6 References

View all (21) LILRB3 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Published Figures (4)
Advanced Verification (1)

LILRB3 Antibody in Western Blot, Immunocytochemistry, Immunoprecipitation (WB, ICC/IF, IP)

FIGURE: 1 / 5

LILRB3 Antibody (MA5-24049) in WB, ICC/IF, IP

Nature communications 2023 - Hepatic PirB is mainly expressed in monocyte-derived macrophages (MDMs). a PirB mRNA expression in different tissues ( n = 4). b , c Flow cytometry (FCM) and quantification of hepatic cells in the livers of the indicated mice ( n = 6 mice/group). d PirB mRNA expression in different hepatic cells ( n = 3). e Flow cytometry (FCM) of hepatic macrophages of the indicated groups. f Flow cytometry (FCM) of PirB ... View More

LILRB3 Antibody in Western Blot, Immunocytochemistry, Immunohistochemistry (WB, ICC/IF, IHC)

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Product Details

MA5-24049

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Flow Cytometry (Flow)

2.5 µg per million cells

Immunoprecipitation (IP)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Mouse

Published species

Mouse

Host/Isotype

Rat / IgG2a

Class

Monoclonal

Type

Antibody

Clone

326414

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse PIR-B Gly24-Gly635

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2608224

Product Specific Information

In Western blots, this antibody does not cross-react with recombinant mouse PIR-A.

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis.

Nature communications

Li DP,Huang L,Kan RR,Meng XY,Wang SY,Zou HJ,Guo YM,Luo PQ,Pan LM,Xiang YX,Mao BB,Xie YY,Wang ZH,Yang M,He R,Yang Y,Liu ZL,Xie JH,Ma DL,Zhang BP,Shao SY,Chen X,Xu SM,He WT,Li WJ,Chen Y,Yu XF

MA5-24049 was used in Immunoprecipitation to demonstrate that PirB/LILRB2 regulates the migration of macrophages during NASH by binding with its ligand angiopoietin-like protein 8.

Sat Jul 22 00:00:00 UTC 2023

LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis.

Nature communications

Li DP,Huang L,Kan RR,Meng XY,Wang SY,Zou HJ,Guo YM,Luo PQ,Pan LM,Xiang YX,Mao BB,Xie YY,Wang ZH,Yang M,He R,Yang Y,Liu ZL,Xie JH,Ma DL,Zhang BP,Shao SY,Chen X,Xu SM,He WT,Li WJ,Chen Y,Yu XF

MA5-24049 was used in Immunoprecipitation to demonstrate that PirB/LILRB2 regulates the migration of macrophages during NASH by binding with its ligand angiopoietin-like protein 8.

Sat Jul 22 00:00:00 UTC 2023

LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis.

Nature communications

Li DP,Huang L,Kan RR,Meng XY,Wang SY,Zou HJ,Guo YM,Luo PQ,Pan LM,Xiang YX,Mao BB,Xie YY,Wang ZH,Yang M,He R,Yang Y,Liu ZL,Xie JH,Ma DL,Zhang BP,Shao SY,Chen X,Xu SM,He WT,Li WJ,Chen Y,Yu XF

MA5-24049 was used in Immunoprecipitation to demonstrate that PirB/LILRB2 regulates the migration of macrophages during NASH by binding with its ligand angiopoietin-like protein 8.

Sat Jul 22 00:00:00 UTC 2023

LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis.

Nature communications

Li DP,Huang L,Kan RR,Meng XY,Wang SY,Zou HJ,Guo YM,Luo PQ,Pan LM,Xiang YX,Mao BB,Xie YY,Wang ZH,Yang M,He R,Yang Y,Liu ZL,Xie JH,Ma DL,Zhang BP,Shao SY,Chen X,Xu SM,He WT,Li WJ,Chen Y,Yu XF

MA5-24049 was used in Immunoprecipitation to demonstrate that PirB/LILRB2 regulates the migration of macrophages during NASH by binding with its ligand angiopoietin-like protein 8.

Sat Jul 22 00:00:00 UTC 2023

Angptl8 mediates food-driven resetting of hepatic circadian clock in mice.

Nature communications

Chen S,Feng M,Zhang S,Dong Z,Wang Y,Zhang W,Liu C

MA5-24049 was used in Western Blotting to study the role of Angptl8 in the circadian rhythm of the liver in response to food.

Tue Aug 06 00:00:00 UTC 2019

Angptl8 mediates food-driven resetting of hepatic circadian clock in mice.

Nature communications

Chen S,Feng M,Zhang S,Dong Z,Wang Y,Zhang W,Liu C

MA5-24049 was used in Western Blotting to study the role of Angptl8 in the circadian rhythm of the liver in response to food.

Tue Aug 06 00:00:00 UTC 2019

Angptl8 mediates food-driven resetting of hepatic circadian clock in mice.

Nature communications

Chen S,Feng M,Zhang S,Dong Z,Wang Y,Zhang W,Liu C

MA5-24049 was used in Western Blotting to study the role of Angptl8 in the circadian rhythm of the liver in response to food.

Tue Aug 06 00:00:00 UTC 2019

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LILRB3 Monoclonal Antibody (326414)

LILRB3 Antibody (MA5-24049) in WB, ICC/IF, IP

Product Details

MA5-24049

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Performance Guarantee

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