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Immunogen sequence: LHEAYKNARS QEEAEGILQQ YIERFTISEA VLERLEMPKI LERSHSTEPN LSSFLNDPNP MKYLRQQSLP PPKFTATVET TIARASV
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
Actin stress fibers-associated protein that activates non-muscle myosin IIa. Activates the non-muscle myosin IIa complex by promoting the phosphorylation of its regulatory subunit MRLC/MYL9. Through the activation of non-muscle myosin IIa, positively regulates actin stress fibers assembly and stabilizes focal adhesions. It therefore negatively regulates cell spreading and cell migration. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: LIM and calponin homology domains-containing protein 1
Gene Aliases: KIAA1102; LIMCH1; LIMCH1A; LMO7B
UniProt ID: (Human) Q9UPQ0
Entrez Gene ID: (Human) 22998
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