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Invitrogen
LIMS2 Polyclonal Antibody
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FIGURE: 1 / 1
LIMS2 Antibody (PA5-109916) in WB
Western blot analysis of LIMS2 in extracts of various cell lines. Samples were incubated with LIMS2 Polyclonal antibody (Product # PA5-109916) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
Product Details
PA5-109916
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-341 of human LIMS2 (NP_001154875.1).
Conjugate
Form
Liquid
Concentration
2.19 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855327
Product Specific Information
Immunogen sequence: MTGSNMSDAL ANAVCQRCQA RFSPAERIVN SNGELYHEHC FVCAQCFRPF PEGLFYEFEG RKYCEHDFQM LFAPCCGSCG EFIIGRVIKA MNNNWHPGCF RCELCDVELA DLGFVKNAGR HLCRPCHNRE KAKGLGKYIC QRCHLVIDEQ PLMFRSDAYH PDHFNCTHCG KELTAEAREL KGELYCLPCH DKMGVPICGA CRRPIEGRVV NALGKQWHVE HFVCAKCEKP FLGHRHYEKK GLAYCETHYN QLFGDVCYNC SHVIEGDVVS ALNKAWCVSC FSCSTCNSKL TLKNKFVEFD MKPVCKRCYE KFPLELKKRL KKLSELTSRK AQPKATDLNS A
Target Information
Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Plays a role in modulating cell spreading and migration.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ILK-binding protein; LIM and senescent cell antigen-like domains 2; LIM and senescent cell antigen-like-containing domain protein 2; LIM-like protein 2; LIM-type zinc finger domains 2; Particularly interesting new Cys-His protein 2; PINCH-2
Gene Aliases: LGMD2W; LIMS2; PINCH-2; PINCH2
UniProt ID: (Human) Q7Z4I7
Entrez Gene ID: (Human) 55679, (Rat) 361303
single organismal cell-cell adhesion
negative regulation of apoptotic process
cell-cell junction organization
negative regulation of epithelial cell proliferation
negative regulation of neural precursor cell proliferation
negative regulation of hepatocyte proliferation
positive regulation of integrin-mediated signaling pathway
cell junction assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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