Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
LIPC Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
21133-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LIPC Fusion Protein Ag15538 (213-463 aa encoded by BC146659)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: DASFVDAIH TFTREHMGLS VGIKQPIGHY DFYPNGGSFQ PGCHFLELYR HIAQHGFNAI TQTIKCSHER SVHLFIDSLL HAGTQSMAYP CGDMNSFSQG LCLSCKKGRC NTLGYHVRQE PRSKSKRLFL VTRAQSPFKV YHYQLKIQFI NQTETPIQTT FTMSLLGTKE KMQKIPITLG KGIASNKTYS FLITLDVDIG ELIMIKFKWE NSAVWANVWD TVQTIIPWST GPRHSGLVLK TIRVKAGETQ QR (213-463 aa encoded by BC146659)
Target Information
The Lipase family belongs to one of the most robust genetic superfamilies found in living organisms that includes esterases and thioesterases. Lipase gene products are related by tertiary structure rather than primary amino acid sequence. Balancing the composition and the transport of lipoproteins in human plasma is essential for normal body function and is mediated in part by Hepatic Lipase, also known as HL or LIPC. Rare deficiencies in Hepatic Lipase have been identified in humans which lead to pathologic levels of circulating lipoprotein particles; this condition is associated with coronary artery disease (CAD). Hepatic Lipase is regulated by thyroid hormones and has a dual function as a triglyceride hydrolase and a ligand/bridging factor for receptor-mediated lipoprotein uptake. Hepatic Lipase localizes to the endothelial surfaces of extrahepatic tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: hepatic lipase; Hepatic triacylglycerol lipase; HL; lipase C; Lipase member C; lipase, hepatic; Lysophospholipase; Phospholipase A1; Triacylglycerol lipase
Gene Aliases: AI256194; HDLCQ12; HL; Hpl; HTGL; LIPC; LIPH
UniProt ID: (Human) P11150, (Mouse) P27656
Entrez Gene ID: (Human) 3990, (Rat) 24538, (Mouse) 15450
phospholipase activity
lysophospholipase activity
triglyceride lipase activity
heparin binding
lipid binding
phosphatidylcholine 1-acylhydrolase activity
transferase activity, transferring acyl groups
low-density lipoprotein particle binding
apolipoprotein binding
heparan sulfate proteoglycan binding
acylglycerol lipase activity
lipase activity
chylomicron binding
carboxylic ester hydrolase activity
protein binding
hydrolase activity
response to hypoxia
liver development
fatty acid biosynthetic process
phosphatidylserine metabolic process
circadian rhythm
cholesterol metabolic process
response to carbohydrate
response to acetate
heparan sulfate proteoglycan biosynthetic process
triglyceride catabolic process
response to nutrient levels
response to magnesium ion
cellular response to hormone stimulus
chylomicron remodeling
very-low-density lipoprotein particle remodeling
intermediate-density lipoprotein particle remodeling
low-density lipoprotein particle remodeling
high-density lipoprotein particle remodeling
chylomicron remnant clearance
low-density lipoprotein particle clearance
phosphatidylcholine catabolic process
response to drug
cholesterol homeostasis
response to amino acid
response to peptide hormone
reverse cholesterol transport
lipid digestion
phosphatidylethanolamine metabolic process
phosphatidic acid metabolic process
glycerophospholipid catabolic process
response to copper ion
developmental growth
protein oligomerization
response to glucocorticoid
response to calcium ion
triglyceride homeostasis
response to fatty acid
fatty acid metabolic process
triglyceride metabolic process
response to hormone
response to inorganic substance
response to organic cyclic compound
cholesterol transport
response to lipid
neutral lipid catabolic process
phosphatidylcholine metabolic process
regulation of plasma lipoprotein particle levels
lipid metabolic process
lipid catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support