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Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 93%; Rat: 100%
The process of transferring lipoic acid to proteins is a two-step process. The first step is the activation of lipoic acid by lipoate-activating enzyme to form lipoyl-AMP. For the second step, LIPT1 transfers the lipoyl moiety to apoproteins.The process of transferring lipoic acid to proteins is a two-step process. The first step is the activation of lipoic acid by lipoate-activating enzyme to form lipoyl-AMP. For the second step, the protein encoded by this gene transfers the lipoyl moiety to apoproteins. Alternative splicing in the 5' UTR of this gene results in five transcript variants that encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Lipoate biosynthesis protein; Lipoate-protein ligase; Lipoyl amidotransferase LIPT1, mitochondrial; Lipoyl ligase; Lipoyltransferase 1
Gene Aliases: LIPT1; LIPT1D
UniProt ID: (Human) Q9Y234
Entrez Gene ID: (Human) 51601
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