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Invitrogen
LMAN1 Monoclonal Antibody (2B4)
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Product Details
MA5-49065
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2B4
Immunogen
Purified mouse MBL-A
Conjugate
Form
Liquid
Concentration
100 µg/mL
Purification
Protein G
Storage buffer
PBS with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3091128
Product Specific Information
The monoclonal antibody 2B4 is a calcium-dependent antibody.
Target Information
The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ER-Golgi intermediate compartment 53 kDa protein; Lectin mannose-binding 1; p58; Protein ERGIC-53
Gene Aliases: 2610020P13Rik; AI326273; AU043785; C730041J05; ERGIC53; F5F8D; gp58; Lman1; MCFD1; MR60; P58
UniProt ID: (Mouse) Q9D0F3
Entrez Gene ID: (Mouse) 70361
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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