Product References
WITHDRAWN: Dual targeting of mitochondrial Lon peptidase 1 and chymotrypsin-like protease by small molecule BT317, as potential therapeutics in malignant astrocytomas.
bioRxiv : the preprint server for biology
Douglas C,Jain S,Lomeli N,Di K,Nandwana NK,Mohammed AS,Vu T,Pham J,Lepe J,Kenney MC,Das B,Bota DA
Thu May 23 00:00:00 UTC 2024
WITHDRAWN: LonP1 Drives Proneural Mesenchymal Transition in IDH1-R132H Diffuse Glioma.
bioRxiv : the preprint server for biology
Douglas C,Lomeli N,Vu T,Pham J,Bota DA
Thu May 23 00:00:00 UTC 2024
FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis.
bioRxiv : the preprint server for biology
Wu J,Subbaiah KCV,Hedaya O,Chen S,Munger J,Tang WHW,Yan C,Yao P
Mon May 22 00:00:00 UTC 2023
The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78/BiP to induce unfolded protein response-mediated apoptosis in myeloma.
Molecular oncology
Luo G,Aldridge K,Chen T,Aslot V,Kim BG,Han EH,Singh N,Li S,Xiao TS,Sporn MB,Letterio JJ
Fri Dec 01 00:00:00 UTC 2023
SIRT6 attenuates LPS-induced inflammation and apoptosis of lung epithelial cells in acute lung injury through ACE2/STAT3/PIM1 signaling.
Immunity, inflammation and disease
Yang J,Chen X
Wed Mar 01 00:00:00 UTC 2023
A cytosolic surveillance mechanism activates the mitochondrial UPR.
Nature
Sutandy FXR,Gößner I,Tascher G,Münch C
Thu Jun 01 00:00:00 UTC 2023
Decreased LONP1 expression contributes to DNA damage and meiotic defects in oocytes.
Molecular reproduction and development
Liu C,Xu M,Guan Y,Li L,Liu W,Guo B,Sheng X,Zhang Y,Zhou J,Zhen X,Yan G,Sun H,Ding L
Thu Jun 01 00:00:00 UTC 2023
Excessive ER-phagy contributes to ochratoxin A-induced apoptosis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Deng H,Chen W,Zhang B,Zhang Y,Han L,Zhang Q,Yao S,Wang H,Shen XL
Thu Jun 01 00:00:00 UTC 2023
Inhibition of human peptide deformylase by actinonin sensitizes glioblastoma cells to temozolomide chemotherapy.
Experimental cell research
Lan B,Zhao H,He Y,Zhao Z,Wang N,Gao Y
Tue Nov 15 00:00:00 UTC 2022
The mitochondrial UPR regulator ATF5 promotes intestinal barrier function via control of the satiety response.
Cell reports
Chamseddine D,Mahmud SA,Westfall AK,Castoe TA,Berg RE,Pellegrino MW
Tue Dec 13 00:00:00 UTC 2022
Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength.
Nature communications
Xu Z,Fu T,Guo Q,Zhou D,Sun W,Zhou Z,Chen X,Zhang J,Liu L,Xiao L,Yin Y,Jia Y,Pang E,Chen Y,Pan X,Fang L,Zhu MS,Fei W,Lu B,Gan Z
Wed Feb 16 00:00:00 UTC 2022
Protein import motor complex reacts to mitochondrial misfolding by reducing protein import and activating mitophagy.
Nature communications
Michaelis JB,Brunstein ME,Bozkurt S,Alves L,Wegner M,Kaulich M,Pohl C,Münch C
Fri Sep 02 00:00:00 UTC 2022
A CHCHD6-APP axis connects amyloid and mitochondrial pathology in Alzheimer's disease.
Acta neuropathologica
Shang Y,Sun X,Chen X,Wang Q,Wang EJ,Miller E,Xu R,Pieper AA,Qi X
Tue Nov 01 00:00:00 UTC 2022
Inhibition of mitochondrial LonP1 protease by allosteric blockade of ATP binding and hydrolysis via CDDO and its derivatives.
The Journal of biological chemistry
Lee J,Pandey AK,Venkatesh S,Thilagavathi J,Honda T,Singh K,Suzuki CK
Tue Mar 01 00:00:00 UTC 2022
Metformin increases the radiosensitivity of non-small cell lung cancer cells by destabilizing NRF2.
Biochemical pharmacology
Sun X,Dong M,Gao Y,Wang Y,Du L,Liu Y,Wang Q,Ji K,He N,Wang J,Zhang M,Gu Y,Song H,Zhai H,Feng L,Xu C,Liu Q
Sun May 01 00:00:00 UTC 2022
Mitofusin 1 and 2 regulation of mitochondrial DNA content is a critical determinant of glucose homeostasis.
Nature communications
Sidarala V,Zhu J,Levi-D'Ancona E,Pearson GL,Reck EC,Walker EM,Kaufman BA,Soleimanpour SA
Fri Apr 29 00:00:00 UTC 2022
UBXD8 mediates mitochondria-associated degradation to restrain apoptosis and mitophagy.
EMBO reports
Zheng J,Cao Y,Yang J,Jiang H
Thu Oct 06 00:00:00 UTC 2022
Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis.
Chinese medicine
Li X,Zhao T,Gu J,Wang Z,Lin J,Wang R,Duan T,Li Z,Dong R,Wang W,Hong KF,Liu Z,Huang W,Gui D,Zhou H,Xu Y
Sat Feb 12 00:00:00 UTC 2022
Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism.
Nature communications
Bussi C,Heunis T,Pellegrino E,Bernard EM,Bah N,Dos Santos MS,Santucci P,Aylan B,Rodgers A,Fearns A,Mitschke J,Moore C,MacRae JI,Greco M,Reinheckel T,Trost M,Gutierrez MG
Mon Nov 28 00:00:00 UTC 2022
Inhibition of High-Temperature Requirement Protein A2 Protease Activity Represses Myogenic Differentiation via UPRmt.
International journal of molecular sciences
Sun H,Shen L,Zhang P,Lin F,Ma J,Wu Y,Yu H,Sun L
Tue Oct 04 00:00:00 UTC 2022
Mitochondria-originated redox signalling regulates KLF-1 to promote longevity in Caenorhabditis elegans.
Redox biology
Hermeling JC,Herholz M,Baumann L,Cores EC,Zečić A,Hoppe T,Riemer J,Trifunovic A
Thu Dec 01 00:00:00 UTC 2022
Mitochondrial proteostasis stress in muscle drives a long-range protective response to alleviate dietary obesity independently of ATF4.
Science advances
Guo Q,Xu Z,Zhou D,Fu T,Wang W,Sun W,Xiao L,Liu L,Ding C,Yin Y,Zhou Z,Sun Z,Zhu Y,Zhou W,Jia Y,Xue J,Chen Y,Chen XW,Piao HL,Lu B,Gan Z
Fri Jul 29 00:00:00 UTC 2022
Mitochondrial proteostasis stress in muscle drives a long-range protective response to alleviate dietary obesity independently of ATF4.
Science advances
Guo Q,Xu Z,Zhou D,Fu T,Wang W,Sun W,Xiao L,Liu L,Ding C,Yin Y,Zhou Z,Sun Z,Zhu Y,Zhou W,Jia Y,Xue J,Chen Y,Chen XW,Piao HL,Lu B,Gan Z
Fri Jul 29 00:00:00 UTC 2022
The mitochondrial protease LONP1 maintains oocyte development and survival by suppressing nuclear translocation of AIFM1 in mammals.
EBioMedicine
Sheng X,Liu C,Yan G,Li G,Liu J,Yang Y,Li S,Li Z,Zhou J,Zhen X,Zhang Y,Diao Z,Hu Y,Fu C,Yao B,Li C,Cao Y,Lu B,Yang Z,Qin Y,Sun H,Ding L
Sat Jan 01 00:00:00 UTC 2022
The parkinsonian LRRK2 R1441G mutation shows macroautophagy-mitophagy dysregulation concomitant with endoplasmic reticulum stress.
Cell biology and toxicology
Yakhine-Diop SMS,Rodríguez-Arribas M,Canales-Cortés S,Martínez-Chacón G,Uribe-Carretero E,Blanco-Benítez M,Duque-González G,Paredes-Barquero M,Alegre-Cortés E,Climent V,Aiastui A,López de Munain A,Bravo-San Pedro JM,Niso-Santano M,Fuentes JM,González-Polo RA
Sat Oct 01 00:00:00 UTC 2022
Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids.
Molecular psychiatry
Pérez MJ,Ivanyuk D,Panagiotakopoulou V,Di Napoli G,Kalb S,Brunetti D,Al-Shaana R,Kaeser SA,Fraschka SA,Jucker M,Zeviani M,Viscomi C,Deleidi M
Fri Oct 01 00:00:00 UTC 2021
Calcitriol increases frataxin levels and restores mitochondrial function in cell models of Friedreich Ataxia.
The Biochemical journal
Britti E,Delaspre F,Sanz-Alcázar A,Medina-Carbonero M,Llovera M,Purroy R,Mincheva-Tasheva S,Tamarit J,Ros J
Fri Jan 15 00:00:00 UTC 2021
ATAD3B is a mitophagy receptor mediating clearance of oxidative stress-induced damaged mitochondrial DNA.
The EMBO journal
Shu L,Hu C,Xu M,Yu J,He H,Lin J,Sha H,Lu B,Engelender S,Guan M,Song Z
Thu Apr 15 00:00:00 UTC 2021
MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control.
Nature cell biology
König T,Nolte H,Aaltonen MJ,Tatsuta T,Krols M,Stroh T,Langer T,McBride HM
Wed Dec 01 00:00:00 UTC 2021
MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control.
Nature cell biology
König T,Nolte H,Aaltonen MJ,Tatsuta T,Krols M,Stroh T,Langer T,McBride HM
Wed Dec 01 00:00:00 UTC 2021
SIRT3-mediated mitochondrial unfolded protein response weakens breast cancer sensitivity to cisplatin.
Genes & genomics
Chen H,Zhang DM,Zhang ZP,Li MZ,Wu HF
Wed Dec 01 00:00:00 UTC 2021
DNA polymerase gamma mutations that impair holoenzyme stability cause catalytic subunit depletion.
Nucleic acids research
Silva-Pinheiro P,Pardo-Hernández C,Reyes A,Tilokani L,Mishra A,Cerutti R,Li S,Rozsivalova DH,Valenzuela S,Dogan SA,Peter B,Fernández-Silva P,Trifunovic A,Prudent J,Minczuk M,Bindoff L,Macao B,Zeviani M,Falkenberg M,Viscomi C
Fri May 21 00:00:00 UTC 2021
Self-assembly of multi-component mitochondrial nucleoids via phase separation.
The EMBO journal
Feric M,Demarest TG,Tian J,Croteau DL,Bohr VA,Misteli T
Mon Mar 15 00:00:00 UTC 2021
Calpain-Inhibitors Protect Frataxin-Deficient Dorsal Root Ganglia Neurons from Loss of Mitochondrial Na+/Ca2+ Exchanger, NCLX, and Apoptosis.
Neurochemical research
Britti E,Delaspre F,Tamarit J,Ros J
Fri Jan 01 00:00:00 UTC 2021
LONP1 and mtHSP70 cooperate to promote mitochondrial protein folding.
Nature communications
Shin CS,Meng S,Garbis SD,Moradian A,Taylor RW,Sweredoski MJ,Lomenick B,Chan DC
Mon Jan 11 00:00:00 UTC 2021
LONP1 and mtHSP70 cooperate to promote mitochondrial protein folding.
Nature communications
Shin CS,Meng S,Garbis SD,Moradian A,Taylor RW,Sweredoski MJ,Lomenick B,Chan DC
Mon Jan 11 00:00:00 UTC 2021
Mitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix.
Communications biology
Matsushima Y,Takahashi K,Yue S,Fujiyoshi Y,Yoshioka H,Aihara M,Setoyama D,Uchiumi T,Fukuchi S,Kang D
Mon Aug 16 00:00:00 UTC 2021
Mitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix.
Communications biology
Matsushima Y,Takahashi K,Yue S,Fujiyoshi Y,Yoshioka H,Aihara M,Setoyama D,Uchiumi T,Fukuchi S,Kang D
Mon Aug 16 00:00:00 UTC 2021
A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.
Cellular and molecular gastroenterology and hepatology
Sun D,Niu Z,Zheng HX,Wu F,Jiang L,Han TQ,Wei Y,Wang J,Jin L
Mon Mar 07 00:00:00 UTC 2022
UPRmt activation protects against MPP+-induced toxicity in a cell culture model of Parkinson's disease.
Biochemical and biophysical research communications
Hu D,Liu Z,Qi X
Fri Sep 10 00:00:00 UTC 2021
An animal model for mitochondrial tyrosyl-tRNA synthetase deficiency reveals links between oxidative phosphorylation and retinal function.
The Journal of biological chemistry
Jin X,Zhang Z,Nie Z,Wang C,Meng F,Yi Q,Chen M,Sun J,Zou J,Jiang P,Guan MX
Mon Aug 02 00:00:00 UTC 2021
LONP1 Regulates Mitochondrial Accumulations of HMGB1 and Caspase-3 in CA1 and PV Neurons Following Status Epilepticus.
International journal of molecular sciences
Kim JE,Park H,Kim TH,Kang TC
Thu Feb 25 00:00:00 UTC 2021
LONP1 Regulates Mitochondrial Accumulations of HMGB1 and Caspase-3 in CA1 and PV Neurons Following Status Epilepticus.
International journal of molecular sciences
Kim JE,Park H,Kim TH,Kang TC
Thu Feb 25 00:00:00 UTC 2021
Loss of high-temperature requirement protein A2 protease activity induces mitonuclear imbalance via differential regulation of mitochondrial biogenesis in sarcopenia.
IUBMB life
Zhou H,Yuan D,Gao W,Tian J,Sun H,Yu S,Wang J,Sun L
Sat Aug 01 00:00:00 UTC 2020
Mitochondrial DNA Haplogroup M7 Confers Disability in a Chinese Aging Population.
Frontiers in genetics
Sun D,Yao S,Wu F,Deng W,Ma Y,Jin L,Wang J,Wang X
Tue Nov 17 00:00:00 UTC 2020
Exogenous Therapeutics of Microrna-29a Attenuates Development of Hepatic Fibrosis in Cholestatic Animal Model through Regulation of Phosphoinositide 3-Kinase p85 Alpha.
International journal of molecular sciences
Yang YL,Wang FS,Lin HY,Huang YH
Thu May 21 00:00:00 UTC 2020
Identification of a Novel c-Myc Inhibitor 7594-0037 by Structure-Based Virtual Screening and Investigation of Its Anti-Cancer Effect on Multiple Myeloma.
Drug design, development and therapy
Yao R,Xie Y,Sun X,Zhang M,Zhou J,Liu L,Gao J,Xu K
Thu Jul 15 00:00:00 UTC 2021
Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1G93A Mice.
International journal of biological sciences
Zhou Q,Zhu L,Qiu W,Liu Y,Yang F,Chen W,Xu R
Mon Nov 02 00:00:00 UTC 2020
A High-Density Human Mitochondrial Proximity Interaction Network.
Cell metabolism
Antonicka H,Lin ZY,Janer A,Aaltonen MJ,Weraarpachai W,Gingras AC,Shoubridge EA
Tue Sep 01 00:00:00 UTC 2020
Toxicity of Necrostatin-1 in Parkinson's Disease Models.
Antioxidants (Basel, Switzerland)
Alegre-Cortés E,Muriel-González A,Canales-Cortés S,Uribe-Carretero E,Martínez-Chacón G,Aiastui A,López de Munain A,Niso-Santano M,Gonzalez-Polo RA,Fuentes JM,Yakhine-Diop SMS
Mon Jun 15 00:00:00 UTC 2020
ATF4 Mediates Mitochondrial Unfolded Protein Response in Alveolar Epithelial Cells.
American journal of respiratory cell and molecular biology
Jiang D,Cui H,Xie N,Banerjee S,Liu RM,Dai H,Thannickal VJ,Liu G
Thu Oct 01 00:00:00 UTC 2020
ATF4 Mediates Mitochondrial Unfolded Protein Response in Alveolar Epithelial Cells.
American journal of respiratory cell and molecular biology
Jiang D,Cui H,Xie N,Banerjee S,Liu RM,Dai H,Thannickal VJ,Liu G
Thu Oct 01 00:00:00 UTC 2020
miR-29a Modulates GSK3β/SIRT1-Linked Mitochondrial Proteostatic Stress to Ameliorate Mouse Non-Alcoholic Steatohepatitis.
International journal of molecular sciences
Yang YL,Wang PW,Wang FS,Lin HY,Huang YH
Sat Sep 19 00:00:00 UTC 2020
Impaired Mitophagy and Protein Acetylation Levels in Fibroblasts from Parkinson's Disease Patients.
Molecular neurobiology
Yakhine-Diop SMS,Niso-Santano M,Rodríguez-Arribas M,Gómez-Sánchez R,Martínez-Chacón G,Uribe-Carretero E,Navarro-García JA,Ruiz-Hurtado G,Aiastui A,Cooper JM,López de Munaín A,Bravo-San Pedro JM,González-Polo RA,Fuentes JM
Mon Apr 01 00:00:00 UTC 2019
Impaired Mitophagy and Protein Acetylation Levels in Fibroblasts from Parkinson's Disease Patients.
Molecular neurobiology
Yakhine-Diop SMS,Niso-Santano M,Rodríguez-Arribas M,Gómez-Sánchez R,Martínez-Chacón G,Uribe-Carretero E,Navarro-García JA,Ruiz-Hurtado G,Aiastui A,Cooper JM,López de Munaín A,Bravo-San Pedro JM,González-Polo RA,Fuentes JM
Mon Apr 01 00:00:00 UTC 2019
TRPC6-Mediated ERK1/2 Activation Increases Dentate Granule Cell Resistance to Status Epilepticus Via Regulating Lon Protease-1 Expression and Mitochondrial Dynamics.
Cells
Kim JE,Park H,Choi SH,Kong MJ,Kang TC
Fri Nov 01 00:00:00 UTC 2019
TRPC6-Mediated ERK1/2 Activation Increases Dentate Granule Cell Resistance to Status Epilepticus Via Regulating Lon Protease-1 Expression and Mitochondrial Dynamics.
Cells
Kim JE,Park H,Choi SH,Kong MJ,Kang TC
Fri Nov 01 00:00:00 UTC 2019
Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation.
The EMBO journal
Ferreira N,Perks KL,Rossetti G,Rudler DL,Hughes LA,Ermer JA,Scott LH,Kuznetsova I,Richman TR,Narayana VK,Abudulai LN,Shearwood AJ,Cserne Szappanos H,Tull D,Yeoh GC,Hool LC,Filipovska A,Rackham O
Mon Dec 16 00:00:00 UTC 2019
Mutant huntingtin inhibits the mitochondrial unfolded protein response by impairing ABCB10 mRNA stability.
Biochimica et biophysica acta. Molecular basis of disease
Fu Z,Liu F,Liu C,Jin B,Jiang Y,Tang M,Qi X,Guo X
Sat Jun 01 00:00:00 UTC 2019
Fidelity of translation initiation is required for coordinated respiratory complex assembly.
Science advances
Rudler DL,Hughes LA,Perks KL,Richman TR,Kuznetsova I,Ermer JA,Abudulai LN,Shearwood AJ,Viola HM,Hool LC,Siira SJ,Rackham O,Filipovska A
Sun Dec 01 00:00:00 UTC 2019
Glucose-regulated protein 75 in foodborne disease models induces renal tubular necrosis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yang X,Li Y,Zheng L,He X,Luo Y,Huang K,Xu W
Fri Nov 01 00:00:00 UTC 2019
Activation of Mitochondrial Unfolded Protein Response in SHSY5Y Expressing APP Cells and APP/PS1 Mice.
Frontiers in cellular neuroscience
Shen Y,Ding M,Xie Z,Liu X,Yang H,Jin S,Xu S,Zhu Z,Wang Y,Wang D,Xu L,Zhou X,Wang P,Bi J
Wed Sep 30 00:00:00 UTC 2020
Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity.
Acta neuropathologica
Hu D,Sun X,Liao X,Zhang X,Zarabi S,Schimmer A,Hong Y,Ford C,Luo Y,Qi X
Sat Jun 01 00:00:00 UTC 2019
CDDO-Me Selectively Attenuates CA1 Neuronal Death Induced by Status Epilepticus via Facilitating Mitochondrial Fission Independent of LONP1.
Cells
Kim JE,Park H,Choi SH,Kong MJ,Kang TC
Mon Aug 05 00:00:00 UTC 2019
CDDO-Me Selectively Attenuates CA1 Neuronal Death Induced by Status Epilepticus via Facilitating Mitochondrial Fission Independent of LONP1.
Cells
Kim JE,Park H,Choi SH,Kong MJ,Kang TC
Mon Aug 05 00:00:00 UTC 2019
TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response.
PLoS genetics
Wang P,Deng J,Dong J,Liu J,Bigio EH,Mesulam M,Wang T,Sun L,Wang L,Lee AY,McGee WA,Chen X,Fushimi K,Zhu L,Wu JY
Wed May 01 00:00:00 UTC 2019
Hispidulin alleviates high-glucose-induced podocyte injury by regulating protective autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wu F,Li S,Zhang N,Huang W,Li X,Wang M,Bai D,Han B
Wed Aug 01 00:00:00 UTC 2018
Hispidulin alleviates high-glucose-induced podocyte injury by regulating protective autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wu F,Li S,Zhang N,Huang W,Li X,Wang M,Bai D,Han B
Wed Aug 01 00:00:00 UTC 2018
Knockout of Mpv17-Like Protein (M-LPH) Gene in Human Hepatoma Cells Results in Impairment of mtDNA Integrity through Reduction of TFAM, OGG1, and LIG3 at the Protein Levels.
Oxidative medicine and cellular longevity
Iida R,Ueki M,Yasuda T
Tue Dec 11 00:00:00 UTC 2018
Knockout of Mpv17-Like Protein (M-LPH) Gene in Human Hepatoma Cells Results in Impairment of mtDNA Integrity through Reduction of TFAM, OGG1, and LIG3 at the Protein Levels.
Oxidative medicine and cellular longevity
Iida R,Ueki M,Yasuda T
Tue Dec 11 00:00:00 UTC 2018
Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology.
Cell reports
Jian F,Chen D,Chen L,Yan C,Lu B,Zhu Y,Chen S,Shi A,Chan DC,Song Z
Tue Jun 05 00:00:00 UTC 2018
Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology.
Cell reports
Jian F,Chen D,Chen L,Yan C,Lu B,Zhu Y,Chen S,Shi A,Chan DC,Song Z
Tue Jun 05 00:00:00 UTC 2018
Lon protease: a novel mitochondrial matrix protein in the interconnection between drug-induced mitochondrial dysfunction and endoplasmic reticulum stress.
British journal of pharmacology
Polo M,Alegre F,Moragrega AB,Gibellini L,Marti-Rodrigo A,Blas-Garcia A,Esplugues JV,Apostolova N
Fri Dec 01 00:00:00 UTC 2017
Lon protease: a novel mitochondrial matrix protein in the interconnection between drug-induced mitochondrial dysfunction and endoplasmic reticulum stress.
British journal of pharmacology
Polo M,Alegre F,Moragrega AB,Gibellini L,Marti-Rodrigo A,Blas-Garcia A,Esplugues JV,Apostolova N
Fri Dec 01 00:00:00 UTC 2017
Zinc enhances the cellular energy supply to improve cell motility and restore impaired energetic metabolism in a toxic environment induced by OTA.
Scientific reports
Yang X,Wang H,Huang C,He X,Xu W,Luo Y,Huang K
Tue Nov 07 00:00:00 UTC 2017
Zinc enhances the cellular energy supply to improve cell motility and restore impaired energetic metabolism in a toxic environment induced by OTA.
Scientific reports
Yang X,Wang H,Huang C,He X,Xu W,Luo Y,Huang K
Tue Nov 07 00:00:00 UTC 2017
miR-542-3p suppresses invasion and metastasis by targeting the proto-oncogene serine/threonine protein kinase, PIM1, in melanoma.
Biochemical and biophysical research communications
Rang Z,Yang G,Wang YW,Cui F
Fri May 27 00:00:00 UTC 2016
miR-542-3p suppresses invasion and metastasis by targeting the proto-oncogene serine/threonine protein kinase, PIM1, in melanoma.
Biochemical and biophysical research communications
Rang Z,Yang G,Wang YW,Cui F
Fri May 27 00:00:00 UTC 2016
A LON-ClpP Proteolytic Axis Degrades Complex I to Extinguish ROS Production in Depolarized Mitochondria.
Cell reports
Pryde KR,Taanman JW,Schapira AH
Tue Dec 06 00:00:00 UTC 2016
A LON-ClpP Proteolytic Axis Degrades Complex I to Extinguish ROS Production in Depolarized Mitochondria.
Cell reports
Pryde KR,Taanman JW,Schapira AH
Tue Dec 06 00:00:00 UTC 2016
Hypermetabolism and hypercatabolism of skeletal muscle accompany mitochondrial stress following severe burn trauma.
American journal of physiology. Endocrinology and metabolism
Ogunbileje JO,Porter C,Herndon DN,Chao T,Abdelrahman DR,Papadimitriou A,Chondronikola M,Zimmers TA,Reidy PT,Rasmussen BB,Sidossis LS
Mon Aug 01 00:00:00 UTC 2016
Mitochondrial Lon is over-expressed in high-grade gliomas, and mediates hypoxic adaptation: potential role of Lon as a therapeutic target in glioma.
Oncotarget
Di K,Lomeli N,Wood SD,Vanderwal CD,Bota DA
Tue Nov 22 00:00:00 UTC 2016
Mitochondrial Lon is over-expressed in high-grade gliomas, and mediates hypoxic adaptation: potential role of Lon as a therapeutic target in glioma.
Oncotarget
Di K,Lomeli N,Wood SD,Vanderwal CD,Bota DA
Tue Nov 22 00:00:00 UTC 2016
Circadian Oscillation of Sulfiredoxin in the Mitochondria.
Molecular cell
Kil IS,Ryu KW,Lee SK,Kim JY,Chu SY,Kim JH,Park S,Rhee SG
Thu Aug 20 00:00:00 UTC 2015
Circadian Oscillation of Sulfiredoxin in the Mitochondria.
Molecular cell
Kil IS,Ryu KW,Lee SK,Kim JY,Chu SY,Kim JH,Park S,Rhee SG
Thu Aug 20 00:00:00 UTC 2015
RNA sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate.
Diabetes
Cnop M,Abdulkarim B,Bottu G,Cunha DA,Igoillo-Esteve M,Masini M,Turatsinze JV,Griebel T,Villate O,Santin I,Bugliani M,Ladriere L,Marselli L,McCarthy MI,Marchetti P,Sammeth M,Eizirik DL
Sun Jun 01 00:00:00 UTC 2014
RNA sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate.
Diabetes
Cnop M,Abdulkarim B,Bottu G,Cunha DA,Igoillo-Esteve M,Masini M,Turatsinze JV,Griebel T,Villate O,Santin I,Bugliani M,Ladriere L,Marselli L,McCarthy MI,Marchetti P,Sammeth M,Eizirik DL
Sun Jun 01 00:00:00 UTC 2014
Central role of Nix in the autophagic response to ochratoxin A.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Shen XL,Zhang B,Liang R,Cheng WH,Xu W,Luo Y,Zhao C,Huang K
Tue Jul 01 00:00:00 UTC 2014
Central role of Nix in the autophagic response to ochratoxin A.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Shen XL,Zhang B,Liang R,Cheng WH,Xu W,Luo Y,Zhao C,Huang K
Tue Jul 01 00:00:00 UTC 2014
The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells.
PloS one
Moore F,Santin I,Nogueira TC,Gurzov EN,Marselli L,Marchetti P,Eizirik DL
Tue Jul 31 00:00:00 UTC 2012
The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells.
PloS one
Moore F,Santin I,Nogueira TC,Gurzov EN,Marselli L,Marchetti P,Eizirik DL
Tue Jul 31 00:00:00 UTC 2012
Decreased activity of the 20S proteasome in the brain white matter and gray matter of patients with multiple sclerosis.
Journal of neurochemistry
Zheng J,Bizzozero OA
Fri Apr 01 00:00:00 UTC 2011
Decreased activity of the 20S proteasome in the brain white matter and gray matter of patients with multiple sclerosis.
Journal of neurochemistry
Zheng J,Bizzozero OA
Fri Apr 01 00:00:00 UTC 2011
