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Alomone Labs, LTD
LPAR2 (EDG4) (extracellular) Polyclonal Antibody
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FIGURE: 1 / 2
LPAR2 (EDG4) (extracellular) Antibody (ALR-032-200UL) in WB
Western blot analysis of rat colon (lanes 1 and 3) and human colorectal adenocarcinoma (colo205) (lanes 2 and 4) lysates: - 1,2. Anti-LPAR2 (EDG4) (extracellular) Antibody (#ALR-032), (1:200).3,4. Anti-LPAR2 (EDG4) (extracellular) Antibody , preincubated with LPAR2/EDG4 (extracellular) Blocking Peptide (#BLP-LR032).
Product Details
ALR-032-200UL
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)NSGKELSLHWRPKD, corresponding to amino acid residues 16-29 of mouse LPA2receptor, Extracellular, N-terminus
Conjugate
Form
Lyophilized
Concentration
0.85 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Edg4 is a Lysophospholipid/Lysosphingolipid Receptor activated by phosphatidic acid (PA) and lysophosphatidic acid (LPA). It enhances the transcription of serum response element (SRE) reporter genes. In CD4(+) T cells, Edg4 may be involved in the control of interleukin-2 secretion. Edg4 expression has been documented in leukocytes, pancreas, spleen, thymus, prostate, and testis. Edg4 expression has also been seen in many cancer cell lines, including those of brain, blood, breast, ovary, cervix, colon, skin, and thyroid. ESTs have been isolated from B-cell/lung/testis, blood, brain, embryo, heart/melanocyte/uterus, liver, placenta, prostate, and skin libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 4; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4; G protein-coupled receptor; LPA receptor 2; LPA receptor EDG4; LPA-2; LPA2 Receptor; Lysophosphatidic acid receptor 2; Lysophosphatidic acid receptor Edg-4; lysophosphatidic acid receptor EDG4; pre-B-cell leukemia transcription factor 4
Gene Aliases: EDG-4; EDG4; IPA2; LPA-2; LPA2; Lpar2; Pbx4; RGD1561336
UniProt ID: (Mouse) Q9JL06
Entrez Gene ID: (Human) 9170, (Rat) 498609, (Mouse) 53978
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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