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Product Details
OSL00014W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from aa region 1020-1070 of rat Latrophilin-2 (LPHN2) conjugated to bluec carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in mouse and human.
Specificity of this antibody: LPHN2.
Target Information
The Latrophilin family of G protein-coupled receptors consists of three members, latrophilin-1, 2 and 3, each of which displays distinct tissue distribution and function. Latrophilin-1, the most characterized member of this family, acts as a receptor for a-latrotoxin, a component of venom from the black widow spider. Binding of a-latrotoxin to latrophilin-1 triggers synaptic vesicle exocytosis via both Ca2+-dependent and -independent mechanisms, resulting in vesicle depletion. Latrophilin-1 is abundant in brain and present in endocrine cells. Latrophilin-3 is also brain-specific, whereas latrophilin-2 expression is ubiquitous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Adhesion G protein-coupled receptor L2; Calcium-independent alpha-latrotoxin receptor 2; calcium-independent alpha-latrotoxin receptor homolog 2; CIRL-2; Cl2aa; latrophilin 1; latrophilin 2; Latrophilin homolog 1; Latrophilin-2; Lectomedin-1
Gene Aliases: ADGRL2; AI450192; Cirl-2; CIRL2; CL2; Cl2ac; Gm619; KIAA0786; LEC1; LPHH1; LPHN2; mKIAA0786
UniProt ID: (Human) O95490, (Rat) O88923
Entrez Gene ID: (Human) 23266, (Mouse) 99633, (Rat) 171447
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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