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Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in mouse and human.
Specificity of this antibody: LPHN2.
The Latrophilin family of G protein-coupled receptors consists of three members, latrophilin-1, 2 and 3, each of which displays distinct tissue distribution and function. Latrophilin-1, the most characterized member of this family, acts as a receptor for a-latrotoxin, a component of venom from the black widow spider. Binding of a-latrotoxin to latrophilin-1 triggers synaptic vesicle exocytosis via both Ca2+-dependent and -independent mechanisms, resulting in vesicle depletion. Latrophilin-1 is abundant in brain and present in endocrine cells. Latrophilin-3 is also brain-specific, whereas latrophilin-2 expression is ubiquitous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adhesion G protein-coupled receptor L2; Calcium-independent alpha-latrotoxin receptor 2; calcium-independent alpha-latrotoxin receptor homolog 2; CIRL-2; Cl2aa; latrophilin 1; latrophilin 2; Latrophilin homolog 1; Latrophilin-2; Lectomedin-1
Gene Aliases: ADGRL2; AI450192; Cirl-2; CIRL2; CL2; Cl2ac; Gm619; KIAA0786; LEC1; LPHH1; LPHN2; mKIAA0786
UniProt ID: (Human) O95490, (Rat) O88923
Entrez Gene ID: (Human) 23266, (Mouse) 99633, (Rat) 171447
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