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LPHN2 Antibody (PA5-75812) in WB
Western blot analysis of LPHN2 in various lysates. Samples were incubated with LPHN2 polyclonal antibody (Product # PA5-75812) using a dilution of 1:500. Lane 1: U-87MG whole cell lysate (40 µg); Lane 2: H1792 whole cell lysate (40 µg); Lane 3: HepG2 whole cell lysate (40 µg).
Product Details
PA5-75812
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues in Human LPHN2
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2719540
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
The Latrophilin family of G protein-coupled receptors consists of three members, latrophilin-1, 2 and 3, each of which displays distinct tissue distribution and function. Latrophilin-1, the most characterized member of this family, acts as a receptor for a-latrotoxin, a component of venom from the black widow spider. Binding of a-latrotoxin to latrophilin-1 triggers synaptic vesicle exocytosis via both Ca2+-dependent and -independent mechanisms, resulting in vesicle depletion. Latrophilin-1 is abundant in brain and present in endocrine cells. Latrophilin-3 is also brain-specific, whereas latrophilin-2 expression is ubiquitous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adhesion G protein-coupled receptor L2; Calcium-independent alpha-latrotoxin receptor 2; CIRL-2; Cl2aa; latrophilin 2; Latrophilin homolog 1; Latrophilin-2; Lectomedin-1
Gene Aliases: ADGRL2; CIRL2; CL2; KIAA0786; LEC1; LPHH1; LPHN2
UniProt ID: (Human) O95490
Entrez Gene ID: (Human) 23266
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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