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Invitrogen
LPL Recombinant Rabbit Monoclonal Antibody (JA22-02)
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Product Details
MA5-32688
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JA22-02
Immunogen
Synthetic peptide within Human Lipoprotein lipase aa 456-475
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2809965
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha lipase; Lipoprotein lipase; LPL; Phospholipase A1
Gene Aliases: HDLCQ11; LIPD; LPL
UniProt ID: (Human) P06858
Entrez Gene ID: (Human) 4023
retinoid metabolic process
fatty acid biosynthetic process
triglyceride metabolic process
phospholipid metabolic process
response to cold
response to glucose
positive regulation of macrophage derived foam cell differentiation
positive regulation of cholesterol storage
positive regulation of sequestering of triglyceride
triglyceride biosynthetic process
triglyceride catabolic process
chylomicron remodeling
very-low-density lipoprotein particle remodeling
lipoprotein metabolic process
response to drug
cholesterol homeostasis
positive regulation of inflammatory response
triglyceride homeostasis
positive regulation of chemokine secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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