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Invitrogen
LRIG1 Polyclonal Antibody
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FIGURE: 1 / 5
LRIG1 Antibody (PA5-47009) in ICC/IF
Immunocytochemistry analysis of LRIG1 in immersion fixed bEnd.3 mouse endothelioma cell line. Samples were incubated in LRIG1 polyclonal antibody (Product # PA5-47009) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red, upper panel) and counterstained with DAPI (blue, lower panel). Specific staining was localized to cytoplasm.
Product Details
PA5-47009
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Published species
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse LRIG1 Ala37-Thr794
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2608300
Product Specific Information
In direct ELISAs, less than 10% cross-reactivity with recombinant human (rh) LRIG1 is observed and less than 5% cross-reactivity with rhLRIG3 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
LRIG1 protein Q96JA1 is coded by a gene on a chromosome band 3p14.3, this region is known to be deleted in various human cancers. LRIG1 is considered to be a tumor suppressor gene in humans. LRIG1 is an integral cell-surface membrane protein that is expressed by specific cells in various human tissues and that its 143-kDa form might be cleaved into 111-kDa and 32-kDa fragments. The LRIG1 protein may inhibit the growth of tumors of glial cells and the down-regulation of the LRIG1 gene may be involved in the development and progression of the tumor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DKFZp586O1624; integral membrane glycoprotein; Leucine-rich repeats and immunoglobulin-like domains protein 1; LIG-1
Gene Aliases: D6Bwg0781e; Img; LIG-1; Lrig1
UniProt ID: (Mouse) P70193
Entrez Gene ID: (Mouse) 16206
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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