Invitrogen

LRP4 Monoclonal Antibody (N207/27)

5 Published Figures

4 References

View all (17) LRP4 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (2)
Published Figures (5)

LRP4 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 7

LRP4 Antibody (MA5-27675) in ICC/IF

Immunofluorescent analysis of LRP4 in human neuroblastoma cell line (SK-N-BE). Sample was fixed with 4% formaldehyde (15 min at RT), incubated with LRP4 monoclonal antibody (Product # MA5-27675) using a dilution of 1:100 (1 hour at RT), and followed by Goat Anti-Mouse 488, Phalloidin Texas Red and DAPI secondary antibody at a dilution of 1:100, 1:1000 (60 min at RT) and 1:5000 (5 min at RT). Images are shown as follows: (A) DAPI (blue) nuclear stain, B) Phalloidin Texas Red F-Actin stain, C) LRP4 (Extracellular) Antibody, D) Merged image. ... View More

LRP4 Antibody in Western Blot, Immunocytochemistry (WB, ICC/IF)

LRP4 Antibody in Western Blot, Immunoprecipitation (WB, IP)

Product Image Gallery

Product Details

MA5-27675

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

1:100

View 1 publication 1 publication

Immunoprecipitation (IP)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

N207/27

Immunogen

Fusion protein amino acids 26- 350 (extracellular N-terminus) of mouse LTP4

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.09% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2735261

Product Specific Information

1 µg/mL of MA5-27675 was sufficient for detection of LRP4 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |Detects the extracellular domain of LRP4 approximately 215kDa. Degradation product can be seen at approximately 150kDa.

This antibody was formerly sold as clone S207-27.

Target Information

This gene encodes a member of the low-density lipoprotein receptor-related protein family. The encoded protein may be a regulator of Wnt signaling. Mutations in this gene are associated with Cenani-Lenz syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Sorting nexin 17 increases low-density lipoprotein receptor-related protein 4 membrane expression: A novel mechanism of acetylcholine receptor aggregation in myasthenia gravis.

Frontiers in immunology

He X,Zhou S,Ji Y,Zhang Y,Lv J,Quan S,Zhang J,Zhao X,Cui W,Li W,Liu P,Zhang L,Shen T,Fang H,Yang J,Zhang Y,Cui X,Zhang Q,Gao F

Published figure using LRP4 monoclonal antibody (Product # MA5-27675) in Immunocytochemistry

Fri Nov 04 00:00:00 UTC 2022

Sorting nexin 17 increases low-density lipoprotein receptor-related protein 4 membrane expression: A novel mechanism of acetylcholine receptor aggregation in myasthenia gravis.

Frontiers in immunology

He X,Zhou S,Ji Y,Zhang Y,Lv J,Quan S,Zhang J,Zhao X,Cui W,Li W,Liu P,Zhang L,Shen T,Fang H,Yang J,Zhang Y,Cui X,Zhang Q,Gao F

Published figure using LRP4 monoclonal antibody (Product # MA5-27675) in Immunocytochemistry

Fri Nov 04 00:00:00 UTC 2022

Sorting nexin 17 increases low-density lipoprotein receptor-related protein 4 membrane expression: A novel mechanism of acetylcholine receptor aggregation in myasthenia gravis.

Frontiers in immunology

He X,Zhou S,Ji Y,Zhang Y,Lv J,Quan S,Zhang J,Zhao X,Cui W,Li W,Liu P,Zhang L,Shen T,Fang H,Yang J,Zhang Y,Cui X,Zhang Q,Gao F

Published figure using LRP4 monoclonal antibody (Product # MA5-27675) in Immunocytochemistry

Fri Nov 04 00:00:00 UTC 2022

Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression.

Gut

Ruivo CF,Bastos N,Adem B,Batista I,Duraes C,Melo CA,Castaldo SA,Campos-Laborie F,Moutinho-Ribeiro P,Morão B,Costa-Pinto A,Silva S,Osorio H,Ciordia S,Costa JL,Goodrich D,Cavadas B,Pereira L,Kouzarides T,Macedo G,Maio R,Carneiro F,Cravo M,Kalluri R,Machado JC,Melo SA

MA5-27675 was used in Western Blotting to provide evidence that CSC EVs use agrin protein to promote Yes1 associated transcriptional regulator (YAP) activation via LDL receptor related protein 4 (LRP-4).

Mon Jan 10 00:00:00 UTC 2022

Bioinformatics

Protein Aliases: Corin; LDLR; LDLR dan; low density lipoprotein receptor-related protein 4; Low-density lipoprotein receptor-related protein 4; LRP-4; Multiple epidermal growth factor-like domains 7

View more View less

Gene Aliases: 6430526J12Rik; CLSS; CMS17; D230026E03; KIAA0816; LRP-4; LRP10; LRP4; mdig; MEGF7; SOST2

View more View less

UniProt ID: (Human) O75096, (Mouse) Q8VI56

View more View less

Entrez Gene ID: (Human) 4038, (Rat) 83469, (Mouse) 228357

View more View less

Function(s)

calcium ion binding protein binding receptor tyrosine kinase binding apolipoprotein binding protein homodimerization activity scaffold protein binding Wnt-protein binding Wnt-activated receptor activity

Process(es)

kidney development hair follicle development endocytosis dorsal/ventral pattern formation proximal/distal pattern formation Wnt signaling pathway negative regulation of ossification BMP signaling pathway odontogenesis of dentin-containing tooth embryonic digit morphogenesis dendrite morphogenesis positive regulation of peptidyl-tyrosine phosphorylation negative regulation of axonogenesis synapse organization synaptic growth at neuromuscular junction protein heterotetramerization limb development skeletal muscle acetylcholine-gated channel clustering negative regulation of canonical Wnt signaling pathway postsynaptic membrane assembly presynaptic membrane assembly positive regulation of presynaptic membrane organization positive regulation of skeletal muscle acetylcholine-gated channel clustering regulation of protein phosphorylation protein localization negative regulation of Wnt signaling pathway embryonic limb morphogenesis receptor clustering anatomical structure development multicellular organism development cell differentiation Wnt signaling pathway involved in dorsal/ventral axis specification canonical Wnt signaling pathway

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

LRP4 Monoclonal Antibody (N207/27)

LRP4 Antibody (MA5-27675) in ICC/IF

Product Details

MA5-27675

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!