LRP5/LRP6 Polyclonal Antibody

protein binding Wnt-protein binding toxin transporter activity Wnt-activated receptor activity coreceptor activity involved in Wnt signaling pathway coreceptor activity involved in canonical Wnt signaling pathway low-density lipoprotein receptor activity receptor binding frizzled binding kinase inhibitor activity apolipoprotein binding identical protein binding protein homodimerization activity molecular_function coreceptor activity

neural tube closure negative regulation of protein phosphorylation pericardium morphogenesis negative regulation of protein kinase activity positive regulation of cytosolic calcium ion concentration chemical synaptic transmission embryonic pattern specification neural crest formation neural crest cell differentiation Wnt signaling pathway single organismal cell-cell adhesion cerebellum morphogenesis thalamus development cerebral cortex development midbrain-hindbrain boundary development negative regulation of smooth muscle cell apoptotic process external genitalia morphogenesis odontogenesis of dentin-containing tooth response to peptide hormone Wnt signaling pathway involved in dorsal/ventral axis specification canonical Wnt signaling pathway involved in neural crest cell differentiation canonical Wnt signaling pathway involved in regulation of cell proliferation positive regulation of cell cycle positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of sequence-specific DNA binding transcription factor activity palate development convergent extension embryonic retina morphogenesis in camera-type eye canonical Wnt signaling pathway face morphogenesis trachea cartilage morphogenesis cellular response to cholesterol dopaminergic neuron differentiation negative regulation of protein serine/threonine kinase activity protein localization to plasma membrane primitive streak formation negative regulation of canonical Wnt signaling pathway receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport Wnt signaling pathway involved in somitogenesis axis elongation involved in somitogenesis positive regulation of canonical Wnt signaling pathway toxin transport beta-catenin destruction complex disassembly midbrain dopaminergic neuron differentiation Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification gastrulation with mouth forming second positive regulation of mesenchymal cell proliferation osteoblast development glucose catabolic process endocytosis cholesterol metabolic process regulation of blood pressure positive regulation of cell proliferation anterior/posterior pattern specification positive regulation of osteoblast proliferation somatic stem cell population maintenance extracellular matrix-cell signaling cell migration involved in gastrulation cholesterol homeostasis embryonic digit morphogenesis regulation of apoptotic process positive regulation of fat cell differentiation negative regulation of osteoblast differentiation positive regulation of mitotic nuclear division bone remodeling regulation of bone remodeling bone marrow development anatomical structure regression retina morphogenesis in camera-type eye bone morphogenesis branching involved in mammary gland duct morphogenesis adipose tissue development cell-cell signaling involved in mammary gland development regulation of canonical Wnt signaling pathway regulation of insulin secretion involved in cellular response to glucose stimulus retinal blood vessel morphogenesis apoptotic process involved in patterning of blood vessels vasculature development regulation of ossification embryonic limb morphogenesis limb morphogenesis regulation of fat cell differentiation embryonic camera-type eye morphogenesis bone development mammary gland duct morphogenesis retina vasculature morphogenesis in camera-type eye somitogenesis heart looping morphogenesis of an epithelium axis elongation regulation of transcription, DNA-templated dorsal/ventral axis specification cerebral cortex cell migration forebrain radial glial cell differentiation forebrain generation of neurons Wnt signaling pathway involved in forebrain neuroblast division neural tube development formation of radial glial scaffolds negative regulation of Wnt signaling pathway forebrain development midbrain development embryonic forelimb morphogenesis embryonic hindlimb morphogenesis post-anal tail morphogenesis regulation of cell proliferation positive regulation of apoptotic process negative regulation of fat cell differentiation positive regulation of ossification positive regulation of bone resorption generation of neurons skeletal system morphogenesis negative regulation of epithelial cell proliferation response to folic acid regulation of cell development mammary placode formation canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation negative regulation of non-canonical Wnt signaling pathway negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis negative regulation of planar cell polarity pathway involved in pericardium morphogenesis negative regulation of planar cell polarity pathway involved in neural tube closure receptor-mediated endocytosis multicellular organism development