Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 1
Sequence of this protein is as follows: MGHKVVVFDI SVIRALWETR VKKHKAWQKK EVERLEKSAL EKIKEEWNFV AECRRKGIPQ AVYCKNGFID TSVRLLDKIE RNTLTRQSSL PKDRGKRSSA FVFELSGEHW TELPDSLKEQ THLREWYISN TLIQIIPTYI QLFQAMRILD LPKNQISHLP AEIGCLKNLK ELNVGFNYLK SIPPELGDCE NLERLDCSGN LELMELPFEL SNLKQVTFVD ISANKFSSVP ICVLRMSNLQ WLDISSNNLT DLPQDIDRLE ELQSFLLYKN KLTYLPYSML NLKKLTLLVV SGDHLVELPT ALCDSSTPLK FVSLMDNPID NAQCEDGNEI MESERDRQHF DKEVMKAYIE DLKERESVPS YTTKVSFSLQ L
This gene encodes a member of the leucine-rich repeat-containing family of proteins, which function in diverse biological pathways. This family member may possibly be a nuclear protein. Similarity to the RAS suppressor protein, as well as expression down-regulation observed in tumor cells, suggests that it may function as a tumor suppressor. The gene is located in the chromosome 3 common eliminated region 1 (C3CER1), a 1.4 Mb region that is commonly deleted in diverse tumors. A related pseudogene has been identified on chromosome 2. [provided by RefSeq, Sep 2011].
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Protein Aliases: Leucine-rich repeat-containing protein 2
Gene Aliases: LRRC2
UniProt ID: (Human) Q9BYS8
Entrez Gene ID: (Human) 79442
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