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Invitrogen
LRRC50 Polyclonal Antibody
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LRRC50 Antibody (PA5-109642) in WB
Western blot analysis of LRRC50 in extracts of Rat testis. Samples were incubated with LRRC50 Polyclonal antibody (Product # PA5-109642) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
Product Details
PA5-109642
Product Specifications
Species Reactivity
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 516-725 of human DNAAF1 (NP_848547.4).
Conjugate
Form
Liquid
Concentration
1.31 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855053
Product Specific Information
Immunogen sequence: VATEGVFVTE LDGTRTEDLE TIRLETKETF CIDDLPDLED DDETGKSLED QNMCFPKIEV ISSLSDDSDP ELDYTSLPVL ENLPTDTLSN IFAVSKDTSK AARVPFTDIF KKEAKRDLEI RKQDTKSPRP LIQELSDEDP SGQLLMPPTC QRDAAPLTSS GDRDSDFLAA SSPVPTESAA TPPETCVGVA QPSQALPTWD LTAFPAPKAS
Target Information
The protein encoded by this gene is cilium-specific and is required for the stability of the ciliary architecture. It is involved in the regulation of microtubule-based cilia and actin-based brush border microvilli. Mutations in this gene are associated with primary ciliary dyskinesia-13.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dynein assembly factor 1, axonemal; Dynein axonemal assembly factor 1; leucine rich repeat containing 50; Leucine-rich repeat-containing protein 50
Gene Aliases: Dnaaf1; Lrrc50; RGD1310542
UniProt ID: (Rat) Q6AYH9
Entrez Gene ID: (Rat) 361419
heart looping
cilium movement
regulation of cilium beat frequency
lung development
determination of pancreatic left/right asymmetry
outer dynein arm assembly
inner dynein arm assembly
motile cilium assembly
cilium morphogenesis
left/right pattern formation
axonemal dynein complex assembly
determination of digestive tract left/right asymmetry
determination of liver left/right asymmetry
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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