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Invitrogen
LRRC50 Polyclonal Antibody
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Product Details
PA5-32025
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human LRRC50. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.96 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2549498
Product Specific Information
Recommended positive controls: mouse testis.
Predicted reactivity: Mouse (87%), Rat (86%), Bovine (88%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is cilium-specific and is required for the stability of the ciliary architecture. It is involved in the regulation of microtubule-based cilia and actin-based brush border microvilli. Mutations in this gene are associated with primary ciliary dyskinesia-13.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dynein (axonemal) assembly factor 1; dynein assembly factor 1, axonemal; Dynein axonemal assembly factor 1; dynein, axonemal, assembly factor 1; leucine rich repeat containing 50; Leucine-rich repeat-containing protein 50; outer row dynein assembly 7 homolog; testicular tissue protein Li 110
Gene Aliases: 4930457P18Rik; CILD13; DNAAF1; LRRC50; ODA7
UniProt ID: (Human) Q8NEP3, (Mouse) Q9D2H9
Entrez Gene ID: (Human) 123872, (Mouse) 68270
heart looping
cilium movement
regulation of cilium beat frequency
lung development
determination of pancreatic left/right asymmetry
outer dynein arm assembly
inner dynein arm assembly
motile cilium assembly
cilium morphogenesis
left/right pattern formation
axonemal dynein complex assembly
determination of digestive tract left/right asymmetry
determination of liver left/right asymmetry
epithelial cilium movement involved in determination of left/right asymmetry
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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