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Proteintech
LRRC8C Polyclonal Antibody
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Product Details
21601-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LRRC8C Fusion Protein Ag16213 (618-803 aa encoded by BC113973)
Conjugate
Form
Liquid
Concentration
0.47 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: DLKENNLKS IEEIVSFQHL RKLTVLKLWH NSITYIPEHI KKLTSLERLS FSHNKIEVLP SHLFLCNKIR YLDLSYNDIR FIPPEIGVLQ SLQYFSITCN KVESLPDELY FCKKLKTLKI GKNSLSVLSP KIGNLLFLSY LDVKGNHFEI LPPELGDCRA LKRAGLVVED ALFETLPSDV REQMKTE (618-803 aa encoded by BC113973 )
Target Information
LRRC8C is a protein coding gene. Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. Plays a redundant role in the efflux of amino acids, such as aspartate and glutamate, in response to osmotic stress. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Factor for adipocyte differentiation 158; hypothetical protein AD158; leucine rich repeat containing 8 family, member C; leucine rich repeat containing 8C; leucine-rich repeat containing 8 family member C; Leucine-rich repeat-containing protein 8C; Volume-regulated anion channel subunit LRRC8C
Gene Aliases: AD158; AI326115; E430036I04Rik; FAD158; LRRC8C; RGD1306585
UniProt ID: (Human) Q8TDW0, (Mouse) Q8R502, (Rat) Q498T9
Entrez Gene ID: (Human) 84230, (Mouse) 100604, (Rat) 289443
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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