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LRRC8D Antibody (PA5-80780) in WB
Western Blot using LRRC8D Polyclonal Antibody (Product # PA5-80780) at 1:500 dilution. Lane A: HeLa Whole Cell Lysate. Lysates/proteins at 30 μg per lane. Secondary antibody: Goat Anti-Rabbit IgG (H+L)/HRP at 1:10,000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 98 kDa.
Product Details
PA5-80780
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to the N-terminus of the Human LRRC8D
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7
Contains
0.03% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2788056
Product Specific Information
This antibody has specificity for Human LRRC8D.
Target Information
Component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8D constitutes a pore-forming subunit or whether it is closely associated with the pore.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HsLRRC8D; leucine rich repeat containing 5; leucine rich repeat containing 8 family; leucine rich repeat containing 8 family, member D; leucine-rich repeat containing 8 family member D; leucine-rich repeat-containing 5; Leucine-rich repeat-containing protein 5; Leucine-rich repeat-containing protein 8D; Volume-regulated anion channel subunit LRRC8D
Gene Aliases: LRRC5; LRRC8D; UNQ213/PRO239
UniProt ID: (Human) Q7L1W4
Entrez Gene ID: (Human) 55144
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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