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LRRFIP2 Antibody (PA5-78569) in IHC (P)
LRRFIP2 Polyclonal Antibody detects LRRFIP2 protein at cytosol on mouse muscle by immunohistochemical analysis. Sample: Paraffin-embedded mouse muscle. LRRFIP2 Polyclonal Antibody (Product # PA5-78569) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-78569
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human LRRFIP2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2736103
Product Specific Information
Predicted Reactivity: Human (100%), Rat (94%), Xenopus laevis (81%), Bovine (95%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The leucine-rich repeat FLI-I-interacting protein 2 (LRRFIP2), like the related protein LRRFIP1, was identified in a yeast two-hybrid system through binding to the LRR domain of human FLI. It can activate the Wnt signaling pathway in cultured cells and is thought to be a component of the Wnt signaling pathway that modulates Wnt signaling through interactions with Disheveled to increase the cellular levels and transcription activity of beta-catenin. LRRFIP2 has recently been characterized as a positive regulator of the TLR4 signaling pathway for activating NF-kappa-B during the early host response to LPS stimulation through binding to the TLR adaptor protein MyD88, and that this interaction with MyD88 is governed by phosphorylation of specific residues in LRRFIP2.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: leucine rich repeat (in FLII) interacting protein 2; Leucine-rich repeat flightless-interacting protein 2; LRR FLII-interacting protein 2
Gene Aliases: 5133400F20Rik; AI850587; HUFI-2; LRRFIP2
UniProt ID: (Human) Q9Y608, (Mouse) Q91WK0
Entrez Gene ID: (Human) 9209, (Mouse) 71268
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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