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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • LRRTM4 Antibodies

          Invitrogen

          LRRTM4 Polyclonal Antibody

          View all (5) LRRTM4 antibodies
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          Cite LRRTM4 Polyclonal Antibody

          • Antibody Testing Data (2)
          LRRTM4 Antibody in Immunohistochemistry (IHC)
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          LRRTM4 Antibody in Immunohistochemistry (IHC)
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          FIGURE: 1 / 2

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          LRRTM4 Antibody (PA5-43452) in IHC

          Immunohistochemistry analysis of rat hippocampal cells using an anti-LRRTM4 polyclonal antibody (Product # PA5-43452). Primary Antibody Dilution:1:200; Secondary Antibody: Anti-rabbit-Cy3; Secondary Antibody Dilution: 1:500. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          LRRTM4 Antibody in Immunohistochemistry (IHC)
          LRRTM4 Antibody in Western Blot (WB)

          Product Details

          PA5-43452

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.2-1 µg/mL
          -

          Immunohistochemistry (IHC)

          1:200
          -
          Product Specifications

          Species Reactivity

          Human, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide directed towards the middle region of human LRRTM4

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Purification

          Affinity Chromatography

          Storage buffer

          PBS with 2% sucrose

          Contains

          0.09% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2606984

          Product Specific Information

          Peptide sequence: FYWLKNFKGN KESTMICAGP KHIQGEKVSD AVETYNICSE VQVVNTERSH

          Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

          Target Information

          The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Little is known about the function of LRRTM4; in mouse, it is expressed in the limb mesenchyme, neural tube, caudal mesoderm and in three distinct regions of the head. Later expression occurs in a subset of the developing sclerotome. Its similarity to other LRRTM family members suggests that LRRTM4 may also play a role in the development and maintenance of the vertebrate nervous system.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: FLJ12568; leucine-rich repeat transmembrane neuronal 4 protein; Leucine-rich repeat transmembrane neuronal protein 4; MGC120633; MGC120636

          View more View less

          Gene Aliases: LRRTM4; RGD1560707; UNQ3075/PRO9907

          View more View less

          UniProt ID: (Human) Q86VH4, (Rat) B4F7C5

          View more View less

          Entrez Gene ID: (Human) 80059, (Rat) 500219

          View more View less

          Function(s)
          protein kinase inhibitor activity heparan sulfate proteoglycan binding
          Process(es)
          negative regulation of protein kinase activity cytokine-mediated signaling pathway negative regulation of JAK-STAT cascade synapse organization neurotransmitter-gated ion channel clustering AMPA glutamate receptor clustering regulation of presynaptic membrane organization
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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