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Invitrogen
LRTOMT Polyclonal Antibody
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FIGURE: 1 / 7
LRTOMT Antibody (PA5-114402) in IHC (P)
Immunohistochemistry analysis of LRTOMT in paraffin-embedded human Lung cancer tissues. Antigen retrieval was performed with citrate buffer (pH6, 20 min). Samples were blocked with 10% goat serum and incubated in LRTOMT polyclonal antibody (Product # PA5-114402) at a dilution of 1 µg/mL (overnight, 4°C), followed by biotinylated goat anti-rabbit IgG (30 min, 37°C) and Strepavidin-Biotin-Complex (SABC) with ... View More
Product Details
PA5-114402
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence of human LRTOMT (RLLTVERDPRTAAVAEKLIRLAGFDEHMVEL).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2884858
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human placenta tissue, human MCF-7 whole cell, human Hela whole cell, human Caco-2 whole cell, human K562 whole cell, human U20S whole cell, human THP-1 whole cell, rat brain tissue, rat ovarian tissue, rat heart tissue, rat lung tissue, mouse brain tissue, mouse lung tissue. IHC: human placenta tissue, human Lung cancer tissue, mouse brain tissue, mouse brain tissue, rat brain tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Required for auditory function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Catechol O-methyltransferase 2; catechol O-methyltransferase 2 {ECO:0000250|UniProtKB:A1Y9I9}; leucine rich transmembrane and 0-methyltransferase domain containing; Leucine-rich repeat-containing protein 51; leucine-rich repeat-containing protein 51 {ECO:0000312|RGD:1565856}; lrrc51 {ECO:0000312|RGD:1565856}; O-methyltransferase domain containing; protein LRTOMT1; Protein LRTOMT2; tomt {ECO:0000312|RGD:1561509}; Transmembrane O-methyltransferase; Transmembrane O-methyltransferase homolog; transmembrane O-methyltransferase {ECO:0000312|RGD:1561509}
Gene Aliases: 1700008D07Rik; CFAP111; COMT2; DFNB63; LRRC51; LRTOMT; PP7517; RGD1561509; RGD1565856; TOMT
UniProt ID: (Human) Q8WZ04, (Mouse) Q9DAK8, (Rat) B6CZ61, (Rat) B6CZ62
Entrez Gene ID: (Human) 220074, (Mouse) 69358, (Rat) 293156, (Rat) 308868
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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