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Invitrogen
LSM1 Recombinant Rabbit Monoclonal Antibody (022)
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FIGURE: 1 / 1
LSM1 Antibody (MA5-29400) in WB
Western Blot using LSM1 Recombinant Rabbit Monoclonal Antibody (22) (Product # MA5-29400) at 1:500 dilution. Lane A: K562 Whole Cell Lysate. Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG H&L (DyLight™ 800) at 1:10,000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 15 kDa. Observed band size: 17 kDa.
Product Details
MA5-29400
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
022
Immunogen
Recombinant Human LSM1 Protein (Met1-Tyr133)
Conjugate
Form
Liquid
Concentration
5 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2785268
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human LSM1.
Target Information
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family. Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cancer-associated Sm protein; Cancer-associated Sm-like; cancer-associated Sm-like protein; cancer‐associated Sm protein; LSM1 homolog, U6 small nuclear RNA associated; LSM1 mRNA degradation associated; LSM1, U6 small nuclear RNA associated; LSM1-like protein U6 small nuclear RNA associated; Small nuclear ribonuclear CaSm; U6 snRNA-associated Sm-like protein LSm1
Gene Aliases: CASM; LSM1; YJL124C
UniProt ID: (Human) O15116
Entrez Gene ID: (Human) 27257
deadenylation-dependent decapping of nuclear-transcribed mRNA
RNA splicing, via transesterification reactions
mRNA processing
RNA splicing
stem cell population maintenance
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
negative regulation of neuron differentiation
histone mRNA catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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