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Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 1 BAC CH230-300K22 (Children's Hospital Oakland Research Institute) complete; 47 kDa actin binding protein; 47 kDa actin-binding protein; 52 kDa phosphoprotein; F-actin binding and cytoskeleton associated protein; leufactin (leukocyte F-actin binding protein); leukocyte specific protein 1; leukocyte-specific protein 1; lsp; lymphocyte specific 1; lymphocyte specific protein 1; Lymphocyte-specific antigen WP34; Lymphocyte-specific protein 1; OTTHUMP00000014138; OTTHUMP00000069614; OTTHUMP00000069615; OTTHUMP00000069616; pp52; S37 protein
Gene Aliases: Lsp-1; LSP1; p50; Pp52; S37; WP34
UniProt ID: (Human) P33241, (Mouse) P19973
Entrez Gene ID: (Human) 4046, (Mouse) 16985, (Rat) 361680
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