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Proteintech
LTBR Polyclonal Antibody
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Product Details
20331-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LTBR Fusion Protein Ag14065 (249-435 aa encoded by BC026262)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: KSHPSLCRK LGSLLKRRPQ GEGPNPVAGS WEPPKAHPYF PDLVQPLLPI SGDVSPVSTG LPAAPVLEAG VPQQQSPLDL TREPQLEPGE QSQVAHGTNG IHVTGGSMTI TGNIYIYNGP VLGGPPGPGD LPATPEPPYP IPEEGDPGPP GLSTPHQEDG KAWHLAETEH CGATPSNRGP RNQFITHD (249-435 aa encoded by BC026262)
Target Information
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: LT beta-R; LT-beta receptor; lymphotoxin B receptor; lymphotoxin beta receptor (TNFR superfamily, member 3); Lymphotoxin-beta receptor; TNF receptor-related protein; TNF-RIII; TNFR-III; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor superfamily member 3; tumor necrosis factor receptor superfamily, member 3; Tumor necrosis factor receptor type III
Gene Aliases: AI256028; CD18; D12S370; LT-BETA-R; Ltar; LTbetaR; LTBR; TNF-R-III; Tnfbr; TNFCR; TNFR-RP; TNFR2-RP; TNFR3; TNFRrp; TNFRSF3
UniProt ID: (Human) P36941, (Mouse) P50284
Entrez Gene ID: (Human) 4055, (Mouse) 17000
apoptotic process
myeloid dendritic cell differentiation
positive regulation of JNK cascade
lymph node development
positive regulation of extrinsic apoptotic signaling pathway
inflammatory response
immune response
signal transduction
multicellular organism development
viral process
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
regulation of cell proliferation
positive regulation of I-kappaB kinase/NF-kappaB signaling
cellular response to mechanical stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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