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Invitrogen
LUM Recombinant Rabbit Monoclonal Antibody (JE11-45)
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Product Details
MA5-34828
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Bovine
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JE11-45
Immunogen
Recombinant protein within Human Lumican aa 172-338
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2848736
Product Specific Information
Positive Control: Jurkat, 293T, Human skin tissue, MCF-7, MG-63, PANC-1, rat kidney tissue, human skin tissue.
Target Information
LUM is a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, this protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. The protein is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Keratan sulfate proteoglycan lumican; KSPG lumican; Lumican; Lumican precursor; lumican proteoglycan
Gene Aliases: LDC; LUM; SLRR2D
UniProt ID: (Human) P51884
Entrez Gene ID: (Human) 4060
axonogenesis
visual perception
response to organic cyclic compound
keratan sulfate biosynthetic process
extracellular matrix organization
collagen fibril organization
positive regulation of transforming growth factor beta1 production
keratan sulfate catabolic process
positive regulation of transcription from RNA polymerase II promoter
cartilage development
response to growth factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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