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Product Details
H00023643-D01P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LY96 (NP_056179.1, 1 a.a. approximately 160 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLPFLFFSTL FSSIFTEAQK QYWVCNSSDA SISYTYCDKM QYPISINVNP CIELKGSKGL LHIFYIPRRD LKQLYFNLYI TVNTMNLPKR KEVICRGSDD DYSFCRALKG ETVNTTISFS FKGIKFSKGK YKCVVEAISG SPEEMLFCLE FVILHQPNSN
Target Information
MD-2 is a gene that encodes a protein involved in the recognition of bacterial lipopolysaccharides (LPS) by the immune system. It is located on chromosome 8 and is part of a larger family of genes that encode for similar proteins. The MD-2 protein forms a complex with Toll-like receptor 4 (TLR4) to recognize and respond to LPS, triggering an immune response. Mutations or variations in the MD-2 gene have been associated with various diseases and conditions, including sepsis and inflammatory disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ESOP-1; Ly-96; Lymphocyte antigen 96; myeloid differentiation factor-2; myeloid differentiation protein-2; Protein MD-2
Gene Aliases: ESOP-1; ESOP1; ly-96; LY96; MD-2; MD2
UniProt ID: (Human) Q9Y6Y9, (Mouse) Q9JHF9
Entrez Gene ID: (Human) 23643, (Mouse) 17087
MyD88-dependent toll-like receptor signaling pathway
MyD88-independent toll-like receptor signaling pathway
inflammatory response
cellular defense response
cell surface receptor signaling pathway
I-kappaB kinase/NF-kappaB signaling
lipopolysaccharide-mediated signaling pathway
positive regulation of lipopolysaccharide-mediated signaling pathway
response to lipopolysaccharide
detection of lipopolysaccharide
positive regulation of tumor necrosis factor production
negative regulation of MyD88-independent toll-like receptor signaling pathway
toll-like receptor 4 signaling pathway
TRIF-dependent toll-like receptor signaling pathway
innate immune response
necroptotic process
apoptotic signaling pathway
pattern recognition receptor signaling pathway
immune system process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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