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Invitrogen
LYPD6B Monoclonal Antibody (634CT7.10.1)
Product Details
MA5-24725
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
634CT7.10.1
Immunogen
KLH conjugated synthetic peptide between 79-108 amino acids from the Central region of human LYPD6B
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2717200
Target Information
Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-3(3):beta-4(2) nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha-3(2):alpha-5:beta-4(2) nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cancer/testis antigen 116; Ly6/PLAUR domain-containing protein 6B
Gene Aliases: 2310010M24Rik; AW049525; CT116; LYPD6B; LYPD7
UniProt ID: (Human) Q8NI32, (Mouse) Q9D7F2
Entrez Gene ID: (Human) 130576, (Mouse) 71897
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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