Proteintech

LYPLA3 Polyclonal Antibody

View all (6) LYPLA3 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Product Details

10863-2-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

LYPLA3 Fusion Protein Ag1304 (1-277 aa encoded by BC011640)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: SYFHTMVES LVGWGYTRGE DVRGAPYDWR RAPNENGPYF LALREMIEEM YQLYGGPVVL VAHSMGNMYT LYFLQRQPQA WKDKYIRAFV SLGAPWGGVA KTLRVLASGD NNRIPVIGPL KIREQQRSAV STSWLLPYNY TWSPEKVFVQ TPTINYTLRD YRKFFQDIGF EDGWLMRQDT EGLVEATMPP GVQLHCLYGT GVPTPDSFYY ESFPDRDPKI CFGDGDGTVN LKSALQCQAW QSRQEHQVLL QELPGSEHIE MLANATTLAY LKRVLLGP (1-277 aa encoded by BC011640)

Target Information

Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 1-O-acylceramide synthase; 1-O-acylceramide synthase {ECO:0000303|PubMed:15294901}; ACS; ACS {ECO:0000303|PubMed:15294901}; group XV phospholipase A2; group XV phospholipase A2 {ECO:0000312|EMBL:AAH98894.1}; LCAT-like lysophospholipase; LCAT-like lysophospholipase {ECO:0000250|UniProtKB:Q8VEB4}; LLPL; LLPL {ECO:0000250|UniProtKB:Q8VEB4}; LPLA2; LPLA2 {ECO:0000303|PubMed:15294901}; Lysophospholipase 3; lysophospholipase 3 (lysosomal phospholipase A2); lysophospholipase 3 {ECO:0000250|UniProtKB:Q8VEB4}; Lysosomal phospholipase A and acyltransferase; Lysosomal phospholipase A2; lysosomal phospholipase A2 {ECO:0000303|PubMed:15294901, ECO:0000312|EMBL:AAS66767.1}; Phospholipase A2 group XV; phospholipase A2, group XV; PLA2G15; pla2g15 {ECO:0000312|Ensembl:ENSRNOP00000026996, ECO:0000312|RGD:1302982}

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Gene Aliases: 1-O-acylceramidesynthase; ACS; C87498; GXVPLA2; LLPL; LPLA2; LYPLA3; PLA2G15; UNQ341/PRO540

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UniProt ID: (Human) Q8NCC3, (Mouse) Q8VEB4, (Rat) Q675A5

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Entrez Gene ID: (Human) 23659, (Mouse) 192654, (Rat) 361401

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Function(s)
lysophospholipase activity phospholipid binding O-acyltransferase activity calcium-independent phospholipase A2 activity dihydrolipoamide branched chain acyltransferase activity sterol O-acyltransferase activity N-acetyltransferase activity palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity carnitine O-acyltransferase activity acetyltransferase activity C-acyltransferase activity palmitoyltransferase activity N-acyltransferase activity acylglycerol O-acyltransferase activity serine O-acyltransferase activity O-acetyltransferase activity O-octanoyltransferase activity octanoyltransferase activity O-palmitoyltransferase activity S-acyltransferase activity S-acetyltransferase activity S-malonyltransferase activity malonyltransferase activity C-palmitoyltransferase activity transferase activity transferase activity, transferring acyl groups succinyltransferase activity N-succinyltransferase activity O-succinyltransferase activity S-succinyltransferase activity sinapoyltransferase activity O-sinapoyltransferase activity hydrolase activity peptidyl-lysine N6-myristoyltransferase activity peptidyl-lysine N6-palmitoyltransferase activity benzoyl acetate-CoA thiolase activity 3-hydroxybutyryl-CoA thiolase activity 3-ketopimelyl-CoA thiolase activity N-palmitoyltransferase activity myristoyltransferase activity acyl-CoA N-acyltransferase activity protein-cysteine S-myristoyltransferase activity protein-cysteine S-acyltransferase activity dihydrolipoamide S-acyltransferase activity glucosaminyl-phosphotidylinositol O-acyltransferase activity ergosterol O-acyltransferase activity lanosterol O-acyltransferase activity naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity 2-methylhexanoyl-CoA C-acetyltransferase activity butyryl-CoA 2-C-propionyltransferase activity 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity L-2-aminoadipate N-acetyltransferase activity UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity keto acid formate lyase activity Ras palmitoyltransferase activity azetidine-2-carboxylic acid acetyltransferase activity peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor acetyl-CoA:L-lysine N6-acetyltransferase
Process(es)
lipid metabolic process fatty acid metabolic process ceramide metabolic process phosphatidylcholine metabolic process glycerophospholipid metabolic process fatty acid catabolic process phosphatidylcholine catabolic process phosphatidylethanolamine catabolic process
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