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FIGURE: 1 / 1
Sequence of this protein is as follows: MGLHLRPYRV GLLPDGLLFL LLLLMLLADP ALPAGRHPPV VLVPGDLGNQ LEAKLDKPTV VHYLCSKKTE SYFTIWLNLE LLLPVIIDCW IDNIRLVYNK TSRATQFPDG VDVRVPGFGK TFSLEFLDPS KSSVGSYFHT MVESLVGWGY TRGEDVRGAP YDWRRAPNEN GPYFLALREM IEEMYQLYGG PVVLVAHSMG NMYTLYFLQR QPQAWKDKYI RAFVSLGAPW GGVAKTLRVL ASGDNNRIPV IGPLKIREQQ RSAVSTSWLL PYNYTWSPEK VFVQTPTINY TLRDYRKFFQ DIGFEDGWLM RQDTEGLVEA TMPPGVQLHC LYGTGVPTPD SFYYESFPDR DPKICFGDGD GTVNLKSALQ CQAWQSRQEH QVLLQELPGS EHIEMLANAT TLAYLKRVLL GP
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities.
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Protein Aliases: 1-O-acylceramide synthase; ACS; LCAT-like lysophospholipase; LLPL; LPLA2; Lysophospholipase 3; lysophospholipase 3 (lysosomal phospholipase A2); Lysosomal phospholipase A and acyltransferase; Lysosomal phospholipase A2; Phospholipase A2 group XV; phospholipase A2, group XV; PLA2G15
Gene Aliases: ACS; GXVPLA2; LLPL; LPLA2; LYPLA3; PLA2G15; UNQ341/PRO540
UniProt ID: (Human) Q8NCC3
Entrez Gene ID: (Human) 23659
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