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Product Details
PA5-66281
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human LYRM1. Recombinant protein control fragment (Product #RP-106966).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2662103
Product Specific Information
Immunogen sequence: MTTATRQEVLG LYRSIFRLAR KWQATSGQME DTIKEKQYIL NEARTLFRKN KNLTDTDLIK
Highest antigen sequence identity to the following orthologs - mouse 87%, rat 92%.
Target Information
LYRM1 was one of many genes identified through a suppression subtractive hybridization comparing their expression in omental adipose tissue of obese patients compared to non-obese individuals. Further study confirms that both mRNA and protein levels of LYRM1 are higher in obese individuals. LYRM1 is widely expressed, with highest levels occurring in adipose and liver tissues. It is thought that LYRM1 promotes preadipocyte proliferation and can inhibit apoptosis of preadipocytes. Ectopic LYRM1 expression did not significantly affect adipogenesis, suggesting that LYRM1 can influence adipose tissue homeostasis by modulating the size of the preadipocyte pool.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: LYR motif-containing protein 1
Gene Aliases: A211C6.1; LYRM1
UniProt ID: (Human) O43325
Entrez Gene ID: (Human) 57149
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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