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LYRM1 Antibody (PA5-90500) in WB
Western blot analysis of LYRM1 in extracts of various cell lines. Samples were incubated with LYRM1 Polyclonal antibody (Product # PA5-90500) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-90500
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-122 of human LYRM1 (NP_0651571)
Conjugate
Form
Liquid
Concentration
0.58 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2806099
Product Specific Information
Immunogen sequence: MTTATRQEVL GLYRSIFRLA RKWQATSGQM EDTIKEKQYI LNEARTLFRK NKNLTDTDLI KQCIDECTAR IEIGLHYKIP YPRPIHLPPM GLTPLRGRGL RSQEKLRKLS KPVYLRSHDE VS; Positive Samples: Mouse testis, Mouse brain; Cellular Location: Nucleus
Target Information
LYRM1 was one of many genes identified through a suppression subtractive hybridization comparing their expression in omental adipose tissue of obese patients compared to non-obese individuals. Further study confirms that both mRNA and protein levels of LYRM1 are higher in obese individuals. LYRM1 is widely expressed, with highest levels occurring in adipose and liver tissues. It is thought that LYRM1 promotes preadipocyte proliferation and can inhibit apoptosis of preadipocytes. Ectopic LYRM1 expression did not significantly affect adipogenesis, suggesting that LYRM1 can influence adipose tissue homeostasis by modulating the size of the preadipocyte pool.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: LYR motif-containing protein 1
Gene Aliases: 1110065L10Rik; 2310004B22Rik; 4930404J24Rik; Lyrm1
UniProt ID: (Mouse) Q9CQB7
Entrez Gene ID: (Mouse) 73919
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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