Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
LZTS2 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
15677-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LZTS2 Fusion Protein Ag8145 (319-669 aa encoded by BC006212)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: PSDEALLHC VLEGKLRDRE AELQQLRDSL DENEATMCQA YEERQRHWQR EREALREDCA AQAQRAQRAQ QLLQLQVFQL QQEKRQLQDD FAQLLQEREQ LERRCATLER EQRELGPRLE ETKWEVCQKS GEISLLKQQL KESQAELVQK GSELVALRVA LREARATLRV SEGRARGLQE AARARELELE ACSQELQRHR QEAEQLREKA GQLDAEAAGL REPPVPPATA DPFLLAESDE AKVQRAAAGV GGSLRAQVER LRVELQRERR RGEEQRDSFE GERLAWQAEK EQVIRYQKQL QHNYIQMYRR NRQLEQELQQ LSLELEAREL ADLGLAEQAP CICLEEITAT EI (319-669 aa encoded by BC006212)
Target Information
LZTS2 is a negative regulator of katanin-mediated microtubule severing and release from the centrosome. LZTS2 is required for central spindle formation and the completion of cytokinesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: hLZTS2; Leucine zipper putative tumor suppressor 2; leucine zipper, putative tumor suppressor 2; Protein LAPSER1; putative tumor suppressor LAPSER1; RP11-108L7.8
Gene Aliases: BC014695; KIAA1813; LAPSER1; LZTS2; mKIAA1813
UniProt ID: (Human) Q9BRK4, (Mouse) Q91YU6
Entrez Gene ID: (Human) 84445, (Mouse) 226154
cytokinesis
kidney development
mitotic nuclear division
negative regulation of cell proliferation
positive regulation of cell death
Wnt signaling pathway
microtubule severing
nuclear export
spindle midzone assembly
negative regulation of canonical Wnt signaling pathway
negative regulation of protein localization to nucleus
cell cycle
negative regulation of Wnt signaling pathway
cell division
renal system development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support