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Invitrogen
LZTS2 Polyclonal Antibody
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Product Details
PA5-72747
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LZTS2 antibody for a 19 amino acid synthetic peptide near the amino terminus of human LZTS2. The immunogen is within amino acids 80 - 130 of LZTS2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2718601
Target Information
LZTS2 is a negative regulator of katanin-mediated microtubule severing and release from the centrosome. LZTS2 is required for central spindle formation and the completion of cytokinesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hLZTS2; Leucine zipper putative tumor suppressor 2; leucine zipper, putative tumor suppressor 2; Protein LAPSER1; putative tumor suppressor LAPSER1; RP11-108L7.8
Gene Aliases: BC014695; KIAA1813; LAPSER1; LZTS2; mKIAA1813
UniProt ID: (Human) Q9BRK4, (Mouse) Q91YU6
Entrez Gene ID: (Human) 84445, (Mouse) 226154
cytokinesis
kidney development
mitotic nuclear division
negative regulation of cell proliferation
positive regulation of cell death
Wnt signaling pathway
microtubule severing
nuclear export
spindle midzone assembly
negative regulation of canonical Wnt signaling pathway
negative regulation of protein localization to nucleus
cell cycle
negative regulation of Wnt signaling pathway
cell division
renal system development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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