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Invitrogen
Laminin alpha-5 Polyclonal Antibody
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Product Details
PA5-49930
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from internal of human LAMA5.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2635383
Product Specific Information
The antibody detects endogenous levels of total Laminin alpha-5 protein.
Target Information
Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: laminin alpha-5 chain; Laminin subunit alpha-5; Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha; RP11-157P1.6
Gene Aliases: [a]5; AA408760; AA408762; AI853660; KIAA0533; KIAA1907; LAMA5; laminin-511; mKIAA0533
UniProt ID: (Human) O15230, (Mouse) Q61001
Entrez Gene ID: (Human) 3911, (Mouse) 16776
branching involved in ureteric bud morphogenesis
morphogenesis of a polarized epithelium
neural crest cell migration
hair follicle development
cell adhesion
integrin-mediated signaling pathway
muscle organ development
organ morphogenesis
morphogenesis of embryonic epithelium
cell migration
regulation of cell adhesion
lung development
regulation of cell migration
substrate adhesion-dependent cell spreading
regulation of cell proliferation
cilium assembly
odontogenesis of dentin-containing tooth
regulation of embryonic development
branching morphogenesis of an epithelial tube
branching involved in salivary gland morphogenesis
establishment of protein localization to plasma membrane
angiogenesis
cytoskeleton organization
cell recognition
cell proliferation
embryo development
cell differentiation
extracellular matrix organization
endothelial cell differentiation
focal adhesion assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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