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Invitrogen
Levodopa Polyclonal Antibody
FIGURE: 1 / 2
Levodopa Antibody (PA5-119575) in ELISA
ELISA of Levodopa in 100 µL (coated at a concentration of 10 µg/mL) of Levodopa carrier protein conjugate. Detection range is 360 ng/mL down to 1.3 ng/mL (coated ligand detection range). Sample was incubated with polyclonal Levodopa antibody (Product # PA5-119575), followed by Rabbit IgG (HRP) with a dilution of 1:2000.
Product Details
PA5-119575
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Chemical
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Levodopa (L-DOPA).
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2913148
Product Specific Information
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Target Information
Levodopa, also known as L-DOPA, is the most widely used drug for the symptomatic treatment of Parkinson's disease, serving as the gold standard for managing the disease's motor symptoms. It functions as a precursor to dopamine, which is deficient in patients with Parkinson's disease due to the degeneration of dopaminergic neurons in the substantia nigra. Once ingested, levodopa crosses the blood-brain barrier and is converted to dopamine, thereby alleviating symptoms such as bradykinesia, rigidity, and tremor. The pharmacokinetics and pharmacodynamics of levodopa have been extensively studied, with various formulations developed to optimize its absorption and reduce side effects. Despite its efficacy, long-term use of levodopa can lead to complications, including motor fluctuations and dyskinesias.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: l-3,4-dihydroxyphenylalanine; L-DOPA
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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