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Product Details
PA1-4966
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bacteria,
Yeast
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Full size LexA recombinant protein.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_667485
Product Specific Information
PA1-4966 detects LexA protein in E.coli and yeast samples.
PA1-4966 has been successfully used in Western blot, immunoprecipitation and immunohistochemical procedures. It is specific for the ~23 kDa LexA protein.
PA1-4966 immunogen is a highly purified recombinant full size LexA protein.
Store at -20ºC.
Target Information
E. coli LexA protein inhibits the transcription of the genes belonging to the SOS regulon that are related to DNA repair and cell division by recognizing and binding to the SOS-box sequence. LexA‘s self-protease activity is promoted by RecA protein which, responding to DNA damage, is activated by its binding to single-strand DNA accumulated in the cells. It is cleaved into two fragments and loses its function as a repressor. As the result, the expression of genes belonging to the SOS regulon is induced, and mutagenic activity in the cells are enhanced.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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