Proteintech

Lumican Polyclonal Antibody

FIGURE: 1 / 3

Lumican Antibody (10677-1-AP) in WB

Jurkat cells were subjected to SDS PAGE followed by western blot with 10677-1-AP (Lumican antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

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Product Details

10677-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 3 publications 3 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Lumican Fusion Protein Ag1106 (1-338 aa encoded by BC007038)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.15 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSLSAFTLF LALIGGTSGQ YYDYDFPLSI YGQSSPNCAP ECNCPESYPS AMYCDELKLK SVPMVPPGIK YLYLRNNQID HIDEKAFENV TDLQWLILDH NLLENSKIKG RVFSKLKQLK KLHINHNNLT ESVGPLPKSL EDLQLTHNKI TKLGSFEGLV NLTFIHLQHN RLKEDAVSAA FKGLKSLEYL DLSFNQIARL PSGLPVSLLT LYLDNNKISN IPDEYFKRFN ALQYLRLSHN ELADSGIPGN SFNVSSLVEL DLSYNKLKNI PTVNENLENY YLEVNQLEKF DIKSFCKILG PLSYSKIKHL RLDGNRISET SLPPDMYECL RVANEVTLN (1-338 aa encoded by BC007038 )

Target Information

LUM is a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, this protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. The protein is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Integrated Strategies of Diverse Feature Selection Methods Identify Aging-Based Reliable Gene Signatures for Ischemic Cardiomyopathy.

Frontiers in molecular biosciences

Song H,Chen S,Zhang T,Huang X,Zhang Q,Li C,Chen C,Chen S,Liu D,Wang J,Tu Y,Wu Y,Liu Y

Sat Mar 19 00:00:00 UTC 2022

Priming integrin α5 promotes human dental pulp stem cells odontogenic differentiation due to extracellular matrix deposition and amplified extracellular matrix-receptor activity.

Journal of cellular physiology

Wang H,Ning T,Song C,Luo X,Xu S,Zhang X,Deng Z,Ma D,Wu B

Thu Aug 01 00:00:00 UTC 2019

Priming integrin α5 promotes human dental pulp stem cells odontogenic differentiation due to extracellular matrix deposition and amplified extracellular matrix-receptor activity.

Journal of cellular physiology

Wang H,Ning T,Song C,Luo X,Xu S,Zhang X,Deng Z,Ma D,Wu B

Thu Aug 01 00:00:00 UTC 2019

Protein expression profiles of human lymph and plasma mapped by 2D-DIGE and 1D SDS-PAGE coupled with nanoLC-ESI-MS/MS bottom-up proteomics.

Journal of proteomics

Clement CC,Aphkhazava D,Nieves E,Callaway M,Olszewski W,Rotzschke O,Santambrogio L

Mon Jan 14 00:00:00 UTC 2013

Protein expression profiles of human lymph and plasma mapped by 2D-DIGE and 1D SDS-PAGE coupled with nanoLC-ESI-MS/MS bottom-up proteomics.

Journal of proteomics

Clement CC,Aphkhazava D,Nieves E,Callaway M,Olszewski W,Rotzschke O,Santambrogio L

Mon Jan 14 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: Keratan sulfate proteoglycan lumican; KSPG lumican; Lumican; Lumican precursor; lumican proteoglycan

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Gene Aliases: Lcn; LDC; LUM; SLRR2D

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UniProt ID: (Human) P51884, (Rat) P51886, (Mouse) P51885

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Entrez Gene ID: (Human) 4060, (Rat) 81682, (Mouse) 17022

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Function(s)

extracellular matrix structural constituent protein binding collagen binding molecular_function

Process(es)

visual perception response to organic cyclic compound collagen fibril organization positive regulation of transcription from RNA polymerase II promoter cartilage development response to growth factor axonogenesis keratan sulfate biosynthetic process extracellular matrix organization positive regulation of transforming growth factor beta1 production keratan sulfate catabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Lumican Polyclonal Antibody

Lumican Antibody (10677-1-AP) in WB

Product Details

10677-1-AP

Western Blot (WB)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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