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Product Details
X1528P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Unique peptide derived from the human lysophospholipid phosphatase 2 protein.
Conjugate
Form
Liquid
Concentration
0.5-2 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
PBS
Contains
0.08% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive control: Transfected HEK-293 cells.
This antibody can be used for Western blotting (10-15 µg/mL). Optimal concentration should be evaluated by serial dilutions. NOTE: Boiling LPP2 with sample buffer will aggregate the protein. Lysates should be prepared by mixing cells with lysis buffer (possibly with extra detergent) to solubilize the protein before adding sample buffer and lysate SHOULD NOT be boiled/heated.
Target Information
Phosphatidic acid phosphatase type 2 (PAP2) was originally identified as a plasma membrane enzyme that catalyses the dephosphorylation of the putative second messenger, phosphatidic acid (PA) to diacylglycerol (DG). Subsequently, multiple isoforms of PAP2 were cloned [2-5]. It was found that these enzymes dephosphorylate a number of lipid phosphates in vitro other than PA, including the potent bioactive lipids, lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P). Therefore, they have been renamed lipid phosphate phosphatases (LPPs). Currently, there are four members of this family called LPP1, LPP1a, LPP2 and LPP3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Lipid phosphate phosphohydrolase 2; LPR3; PAP-2c; PAP2-G; PAP2-gamma; PAP2c; Phosphatidate phosphohydrolase type 2c; Phosphatidic acid phosphatase 2c; phosphatidic acid phosphatase type 2C; phosphatidic acid phosphohydrolase type 2c; Phospholipid phosphatase 2; PRG-2; PRG2; type-2 phosphatidic acid phosphatase-gamma
Gene Aliases: LPP2; PAP-2c; PAP2-g; PLPP2; PPAP2C
UniProt ID: (Human) O43688
Entrez Gene ID: (Human) 8612
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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