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Invitrogen
MA2 Polyclonal Antibody
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Product Details
PA5-81995
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PNMA2. Recombinant protein control fragment (Product #RP-102104).
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2789156
Product Specific Information
Immunogen sequence: KQENANAVLL ELLEDTDVSA IPSEVQGKGG VWKVIFKTPN QDTEFLERLN LFLEKEGQTV SGMFRALGQE GVSPATVPCI SPELLAHLLG QAMAHAPQPL LPMRYRKLRV FSGSAVPAPE EESFEVWLEQ ATEIVKEWPV TEAEKKRWL
Target Information
In patients with cancer, symptoms of limbic and brain-stem dysfunction may result from a para-neoplastic disorder. Two proteins, Ma1 and Ma2, were discovered by presence of autoantibodies against them. Antibodies to Ma1 and Ma2 proteins identify a paraneoplastic disorder that affects the limbic system, brain stem, and cerebellum. These autoantibodies were used to clone Ma2, which codes for a protein (Ma2) that was recognized by serum from the 10 patients, but not by serum from 344 control subjects. Ma2 was selectively expressed by normal brain tissue and by the testicular tumors of the patients. Ma2 shares homology with Ma1, a "brain-testis-cancer" gene related to other para-neoplastic syndromes and tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 40 kDa neuronal protein; Onconeuronal antigen Ma2; Paraneoplastic antigen Ma2; Paraneoplastic neuronal antigen MM2; retrotransposon gag domain containing 2
Gene Aliases: KIAA0883; MA2; MM2; PNMA2; RGAG2
UniProt ID: (Human) Q9UL42
Entrez Gene ID: (Human) 10687
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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