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MACF1 Polyclonal Antibody

MACF1 Antibody in Immunocytochemistry (ICC/IF)

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MACF1 Antibody (13058-1-AP) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed NIH/3T3 cells using 13058-1-AP (MACF1 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

MACF1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

13058-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:100

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MACF1 Fusion Protein Ag3730 (3-305 aa encoded by BC007330)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.18 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: EDEVTRQVA QCKCAKRFQV EQIGENKYRF GDSQQLRLVR ILRSTVMVRV GGGWMALDEF LVKNDPCRAR GRTNIELREK FILPEGASQG MTPFRSRGRR SKPSSRAASP TRSSSSASQS NHSCTSMPSS PATPASGTKT SLQFSRCYDK PWLVNSKAGT PIRDSHSPDL QLPTPEVIPS SGSKLKRPTP TFHSSRTSLA GDTSNSSSPA STGAKTNRAD PKKSASRPGS RAGSRAGSRA SSRRGSDASD FDLLETQSAC SDTSESSAAG GQGNSRRGLN KPSKIPTMSK KTTTASPRTP GPKR (3-305 aa encoded by BC007330)

Target Information

SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Comparison of the mutation patterns between tumor tissue and cell-free DNA in stage IV gastric cancer.

Aging

Kung CY,Fang WL,Hung YP,Huang KH,Chen MH,Chao Y,Lin SC,Li AF,Lo SS,Wu CW

Fri Feb 10 00:00:00 UTC 2023

The genomic landscape of cholangiocarcinoma reveals the disruption of post-transcriptional modifiers.

Nature communications

Zhang Y,Ma Z,Li C,Wang C,Jiang W,Chang J,Han S,Lu Z,Shao Z,Wang Y,Wang H,Jiao C,Wang D,Wu X,Shen H,Wang X,Hu Z,Li X

Wed Jun 01 00:00:00 UTC 2022

MACF1 promotes osteoblast differentiation by sequestering repressors in cytoplasm.

Cell death and differentiation

Hu L,Yin C,Chen D,Wu Z,Liang S,Zhang Y,Huang Z,Liu S,Xu X,Chen Z,Zhang Y,Qian A

Thu Jul 01 00:00:00 UTC 2021

LRP6 promotes invasion and metastasis of colorectal cancer through cytoskeleton dynamics.

Oncotarget

Yao Q,An Y,Hou W,Cao YN,Yao MF,Ma NN,Hou L,Zhang H,Liu HJ,Zhang B

Tue Dec 12 00:00:00 UTC 2017

LRP6 promotes invasion and metastasis of colorectal cancer through cytoskeleton dynamics.

Oncotarget

Yao Q,An Y,Hou W,Cao YN,Yao MF,Ma NN,Hou L,Zhang H,Liu HJ,Zhang B

Tue Dec 12 00:00:00 UTC 2017

BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment.

PLoS genetics

Hsu Y,Garrison JE,Kim G,Schmitz AR,Searby CC,Zhang Q,Datta P,Nishimura DY,Seo S,Sheffield VC

Sun Oct 01 00:00:00 UTC 2017

BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment.

PLoS genetics

Hsu Y,Garrison JE,Kim G,Schmitz AR,Searby CC,Zhang Q,Datta P,Nishimura DY,Seo S,Sheffield VC

Sun Oct 01 00:00:00 UTC 2017

Proteomics-based identification of tumor relevant proteins in lung adenocarcinoma.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhou X,Xue L,Hao L,Liu S,Zhou F,Xiong H,Qi X,Lin D,Shao S

Sun Sep 01 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: 620 kDa actin binding protein; 620 kDa actin-binding protein; ABP620; actin cross-linking family 7; Actin cross-linking family protein 7; actin-crosslinking protein 7; FLJ45612; FLJ46776; macrophin 1; macrophin 1 isoform; Macrophin-1; microtubule-actin cross-linking factor 1; Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5; trabeculin alpha; Trabeculin-alpha

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Gene Aliases: ABP620; ACF7; Aclp7; KIAA0465; KIAA0754; KIAA1251; MACF; MACF1; mKIAA0465; OFC4; R74989

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UniProt ID: (Human) Q9UPN3

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Entrez Gene ID: (Human) 23499, (Mouse) 11426

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Function(s)

actin binding calcium ion binding protein binding microtubule binding ATPase activity poly(A) RNA binding actin filament binding cadherin binding involved in cell-cell adhesion metal ion binding

Process(es)

mesoderm formation posttranslational protein targeting to membrane movement of cell or subcellular component cell cycle arrest establishment or maintenance of cell polarity protein localization regulation of epithelial cell migration Wnt signaling pathway positive regulation of Wnt signaling pathway regulation of microtubule-based process wound healing regulation of focal adhesion assembly Golgi to plasma membrane protein transport positive regulation of axon extension cell-cell adhesion

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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MACF1 Polyclonal Antibody

MACF1 Antibody (13058-1-AP) in ICC/IF

Product Details

13058-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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