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Recommended positive controls: A431, Molt-4, GL261, BCL-1, Raw264.7, PC-12.
Predicted reactivity: Mouse (97%), Rat (97%), Xenopus laevis (86%), Rhesus Monkey (98%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: homolog of yeast MAF1; MAF1 negative regulator of RNA polymerase III; Repressor of RNA polymerase III transcription MAF1 homolog
Gene Aliases: MAF1
UniProt ID: (Human) Q9H063
Entrez Gene ID: (Human) 84232
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