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Invitrogen
MAG Recombinant Rabbit Monoclonal Antibody (PSH02-42)
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FIGURE: 1 / 23
MAG Antibody (MA5-52084) in IHC (P)
Immunohistochemical analysis of MAG was performed using formalin-fixed paraffin-embedded mouse brain and liver tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - Low pH (10X) (Product # 00-4955-58 diluted to 1X solution in water in a decloaking chamber at 110 degree Celsius for 15 minutes... View More
Product Details
MA5-52084
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
PSH02-42
Immunogen
Recombinant protein within human mag aa 1- 536.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3099398
Product Specific Information
Tissue Specificity: central and peripheral nervous system
Positive Control: Mouse brain (no heat) tissue lysate, mouse cerebellum tissue lysate, rat brain (no heat) tissue lysate, rat cerebellum tissue lysate, human cerebellum tissue, mouse brain tissue, mouse cerebellum tissue, mouse hippocampus tissue, rat brain tissue, rat cerebellum tissue, rat hippocampus tissue.
Subcellular Location: Cell membrane.
Predicted band size: 69 kDa.
Target Information
The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1B236; Brain neuron cytoplasmic protein 3; Myelin-associated glycoprotein; S-MAG (C-term.); sialic acid binding Ig-like lectin 4A; Sialic acid-binding Ig-like lectin 4a; sialic acid-binding immunoglobulin-like lectin 4A; Siglec-4a
Gene Aliases: GMA; MAG; S-MAG; SIGLEC-4A; SIGLEC4A; SPG75
UniProt ID: (Human) P20916, (Rat) P07722, (Mouse) P20917
Entrez Gene ID: (Human) 4099, (Rat) 29409, (Mouse) 17136
cell adhesion
nervous system development
negative regulation of neuron projection development
substantia nigra development
negative regulation of neuron differentiation
positive regulation of astrocyte differentiation
cellular response to mechanical stimulus
positive regulation of myelination
negative regulation of axonogenesis
leukocyte migration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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